for Kindle Fire, Apple, Android, Nook, Kobo, PC, Mac, BlackBerry ...

New to eBooks.com?

Learn more

Assessing Bioavailablility of Drug Delivery Systems

Mathematical Modeling

Assessing Bioavailablility of Drug Delivery Systems by Jean-Maurice Vergnaud
Add to cart
US$ 209.95
(If any tax is payable it will be calculated and shown at checkout.)
DEFINITIONS
Drugs (Active Agents) and Their Supply Forms (Dosage Forms)
Biopharmaceutics and Its Goal
Pharmacokinetics
Pharmacodynamics
Liberation of the Drug
Membranes
Bioavailability
Absorption of the Drug in the Blood
Distribution of the Drug
Elimination of the Drug
Therapeutic Index
Determination of the Pharmaceutical Parameters

INTRAVENOUS ADMINISTRATION
Administration of a Single Dose
Repeated Intravenous Injections (DIV)
Continuous Intravenous Infusion (CIV)
Repeated Dosage at Constant Flow Rate

ORAL DOSAGE FORMS WITH IMMEDIATE RELEASE
Single Dose
Effect of the Pharmacokinetic Parameters' Values
Multiple Oral Doses
Area under the Curve with Oral Dosage Forms
Comparison Between Oral and I.V. Drug Delivery

KINETICS OF DRUG RELEASE FROM ORAL SUSTAINED DOSAGE FORMS
Drug Release Controlled by Diffusion
Drug Release Controlled by Erosion
Comparisons and Other Kinetics of Release

BIBLIOGRAPHY ON IN VITRO-IN VIVO CORRELATIONS
General Survey on In Vitro-In Vivo Problems
In Vitro-In Vivo Correlations for Oral Immediate-Release Dosage Forms
In Vitro-In Vivo Correlations with Oral Sustained-Release Dosage Forms

PLASMA DRUG LEVEL WITH ORAL DIFFUSION-CONTROLLED DOSAGE FORMS
Methods of Calculation
Results Obtained for a Single Dose
Sustained Release with Repeated Doses
Prediction of the Characteristics of the Dosage Form

PLASMA DRUG LEVEL WITH EROSION-CONTROLLED DOSAGE FORMS
Method of Calculation
Plasma Drug Profile with a Single Dose
Plasma Drug Profile with Repeated Multidoses
Prediction of the Characteristics of the Dosage Forms

EFFECT OF PATIENT'S NONCOMPLIANCE
Limited Reliability of the Patient
Noncompliance with Erosion-Controlled Dosage Forms
Noncompliance with Diffusion-Controlled Dosage Forms

DRUG TRANSFER IN VARIOUS TISSUES
Drug Transfer into and through the Lung and Bronchial Mucus
Drug Transfer into the Blister Fluid
Drug Transfer into Endocarditis

TRANSDERMAL THERAPEUTIC SYSTEMS
General Mechanisms of Drug Delivery
Overview of the Skin and Its Role
Calculation of the Drug Transport
Results for the Transdermal Delivery of Metropolol
Effect of the Characteristics of the TTS
Effect of the Parameters of the Skin
CRC Press; May 2005
245 pages; ISBN 9781420037852
Read online, or download in secure PDF format
Title: Assessing Bioavailablility of Drug Delivery Systems
Author: Jean-Maurice Vergnaud; Iosif-Daniel Rosca
 
Buy, download and read Assessing Bioavailablility of Drug Delivery Systems (eBook) by Jean-Maurice Vergnaud; Iosif-Daniel Rosca today!