Ireland and the Americas: Culture, Politics, and History aims to broaden the traditional notion of 'Irish-American' beyond Boston, New York, and Chicago. In additional to full coverage of Irish culture in those settings, it reveals the pervasive Irish influence in everything from the settling of the American West, to the spread of Christianity throughout the hemisphere, to Irish involvement in revolutionary movements from the American colonies to Mexico to South America.

In addition, the encyclopedia shows the profound impact of Irish Americans on their homeland, in everything from art and literature informed by the emigrant experience, to efforts by Irish Americans to influence Irish politics. Ranging from colonial times to the present, and informed by the surge of academic interest in the past 30 years, Ireland and the Americas is the definitive resource on the profound ties that bind the cultures of Ireland, the United States, Canada, and Latin America.