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Neurophysiology Study Guide
Audience: Intended for everyone interested in Neurophysiology, particularly undergraduate and graduate life science students, medical students, and nursing students.
Written in clear, concise format.
Difficult concepts are explained in simple terms.
Navigate from Table of Contents or search for the words or phrases
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Use your down-time to prepare for an exam.
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Table of Contents
I. Neurocellular Anatomy
Neuron: Axon | Dendrite | Apical dendrite | Dendritic spine | Afferent nerve | Efferent nerve | Sensory nerve | Motor nerve
Axonal Transport and Growth: Axoplasmic transport | Kinesin | Dynein | Myosin | Growth cone | Axon guidance
Synapse: Synaptic Vesicles | Exocytosis | Endocytosis | Synaptic plasticity | SNARE | Synaptobrevin | Synapsin | NSF | Excitatory synapse | Inhibitory synapse | Electrical synapse | Gap junction
Types of neurons: Pyramidal cell | Betz cell | Purkinje cell | Neuromuscular junction | Muscle spindle | Golgi organ | Motor neuron | Sensory neuron
Glial cell: Astrocyte | Oligodendrocyte | Schwann cell | Myelin | Nodes of Ranvier
Cytoskeleton: Actin | Intermediate filament | Microtubule
II. Membranes And Transport
Membrane Structure: Fluid mosaic model | Detailed Structure
Membrane Components: Phospholipids | Sphingomyelin | Glycolipid | Glycocalix | Cholesterol
Movement of Molecules: Diffusion | Osmosis | Electrochemical gradient
Passive transport: Facilitated diffusion | Ion channel
Active transport: ATP-Dependent Na/K Pump | Proton pump | Antiporter | Symporter
III. Ion Channels
Channels: Ion channel | Gap junction
Voltage-gated: Potassium channel | Sodium channel | BK channel | Inward-rectifier potassium ion channel | Resting channels | Calcium channel
Ligand-gated: NMDA receptor | AMPA receptor | Kainate receptor | Nicotinic acetylcholine receptor | Glycine receptor | GABA receptor
Other ion channels: Cyclic nucleotide-gated | Stretch-activated | G-protein-gated | Light-gated | Gap junction
IV. Electrical Phenomena
Review: Electrical charge | Resistance | Capacitance
Resting Membrane Potential: Ionic Basis | Number of ions involved in generating the resting potential | Equilibrium potential | Other values of membrane potential | Implications | Nernst equation | Goldman equation | Depolarization | Hyperpolarization
Action Potential: Threshold and initiation | Circuit model | Propagation | Refractory period | Evolutionary purpose | Nodes of Ranvier | Reflex arc
Postsynaptic Potential: Excitatory postsynaptic potential | Inhibitory postsynaptic potential | Spatial summation | Temporal summation | Shunting
V. Signal Transduction
Extracellular Signalling - Neurotransmitters and receptors: Acetylcholine | Degradation by acetylcholinesterase | Ach Receptors
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