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Mirror-Image Asymmetry

An Introduction to the Origin and Consequences of Chirality

Mirror-Image Asymmetry by James P. Riehl
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An overview of the importance and consequences of asymmetry frommolecules to the macroscopic world

As scientists have become more capable of probing the structureof three-dimensional objects at the molecular level, the need tounderstand the concept and the consequences of mirror-imageasymmetry—chirality—has increased enormously. Writtenat an introductory level, Mirror-Image Asymmetry provides anoverview of the importance and effects of asymmetry from the atomicand molecular world of physics and chemistry to the organisms andstructures that we see and use in our everyday life. The readerwill develop a broad appreciation of three-dimensional asymmetryfrom the microscopic molecular world to the macroscopic world ofhandedness, automobile driving, windmills, sports, and similarphenomena. The book features:

  • An introduction to basic definitions and the nomenclature ofasymmetric and dissymmetric molecules

  • Up-to-date examples of the importance and consequences ofasymmetry in modern drug applications, current theories of theorigin of asymmetry in nature, and examples of molecular asymmetryin smell, taste, and insect communication

  • Many illustrations, chemical structures, and photographs thatenable the reader to connect the actual asymmetrical structures tothe different phenomena that depend on structural asymmetry

In the 150 years since Louis Pasteur discovered asymmetry inmolecular structures, scientists have made great progress inunderstanding how interactions between chiral molecules influencebiochemical processes. This knowledge is leading to verysophisticated asymmetric synthetic techniques that have greatlybenefitted many research groups especially those in thepharmaceutical industry. This guide to the role of molecular andmacroscopic chirality will inspire students and scientists inchemistry, biology, physics, and drug discovery.

Wiley; April 2011
272 pages; ISBN 9780470588871
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Title: Mirror-Image Asymmetry
Author: James P. Riehl
 
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ISBNs
047058887X
9780470387597
9780470588871