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Cellular Senescence and Tumor Suppression

Cellular Senescence and Tumor Suppression by Peter D. Adams
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As cells mature they naturally stop dividing and enter a period called senescence. But cellular senescence can also be induced prematurely by certain oncogenes involved in cancer development. Cellular senescence, a growth-arrest program that limits the lifespan of mammalian cells and prevents unlimited cell proliferation, is attracting considerable interest because of its links to tumor suppression.
Springer New York; January 2010
273 pages; ISBN 9781441910752
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Title: Cellular Senescence and Tumor Suppression
Author: Peter D. Adams; John M. Sedivy