Protein and Peptide Mass Spectrometry in Drug Discovery
An instrumental analytical method for quantifying the mass andcharacterization of various samples from small molecules to largeproteins, mass spectrometry (MS) has become one of the most widelyused techniques for studying proteins and peptides over the lastdecade. Bringing together the work of experts in academia andindustry, Protein and Peptide Mass Spectrometry in DrugDiscovery highlights current analytical approaches, industrypractices, and modern strategies for the characterization of bothpeptides and proteins in drug discovery.
Illustrating the critical role MS technology plays incharacterizing target proteins and protein products, the methodsused, ion mobility, and the use of microwave radiation to speedproteolysis, the book also covers important emerging applicationsfor neuroproteomics and antigenic peptides. Placing an emphasis onthe pharmaceutical industry, the book stresses practice andapplications, presenting real-world examples covering the mostrecent advances in mass spectrometry, and providing an invaluableresource for pharmaceutical scientists in industry and academia,analytical and bioanalytical chemists, and researchers in proteinscience and proteomics.
448 pages; ISBN 9781118116548
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Title: Protein and Peptide Mass Spectrometry in Drug Discovery
Author: Michael L. Gross; Guodong Chen; Birendra Pramanik
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