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Iron Physiology and Pathophysiology in Humans
Springer 2012; US$ 219.99Iron Physiology and Pathophysiology in Humans provides health professionals in many areas of research and practice with the most up-to-date and well-referenced volume on the importance of iron as a nutrient and its role in health and disease. This important new volume is the benchmark in the complex area of interrelationships between the essentiality... more...
Water Soluble Vitamins
Springer 2011; US$ 189.99The discovery of vitamins in the early 1900s, their later chemical characterization and the clarification of pivotal metabolic functions are sequential aspects of a brilliant chapter in the history of modern nutritional sciences and medicine. The name, derived from "vital-amines", indicates their elementary metabolic key functions in human... more...
Protein Folding and Misfolding
Springer 2011; US$ 99.99Infrared spectroscopy is a new and innovative technology to study protein folding/misfolding events in the broad arsenal of techniques conventionally used in this field. The progress in understanding protein folding and misfolding is primarily due to the development of biophysical methods which permit to probe conformational changes with high kinetic... more...
Adenosine Deaminases Acting on RNA (ADARs) and A-to-I Editing
Springer 2011; US$ 149.99The objective of this "CTMI" volume is to provide readers with a foundation for understanding what ADARs are and how they act to affect gene expression and function. It is becoming increasingly apparent that ADARs may possess roles not only as enzymes that deaminate adenosine to produce inosine in RNA substrates with double-stranded character,... more...
Phosphoinositides II
Springer 2012; US$ 189.99Phosphoinositides play a major role in cellular signaling and membrane organization. During the last three decades we have learned that enzymes turning over phosphoinositides control vital physiological processes and are involved in the initiation and progression of cancer, inflammation, neurodegenerative, cardiovascular, metabolic disease and more.... more...
Microbial Degradation of Xenobiotics
Springer 2011; US$ 139.99Our interest in the microbial biodegradation of xenobiotics has increased many folds in recent years to find out sustainable ways for environmental cleanup. Bioremediation and biotransformation processes harness the naturally occurring ability of microbes to degrade, transform or accumulate a wide range of organic pollutants. Major methodological breakthroughs... more...
Formation and Cooperative Behaviour of Protein Complexes on the Cell Membrane
Springer 2011; US$ 99.99With the aim of providing a deeper insight into possible mechanisms of biological self-organization, this thesis presents new approaches to describe the process of self-assembly and the impact of spatial organization on the function of membrane proteins, from a statistical physics point of view. It focuses on three important scenarios: the assembly... more...
Heteroaromatic Lipoxin A4 Analogues
Springer 2012; US$ 99.99In this thesis Colm Duffy reviews the chemistry and biology of stable lipoxin analogues. Colm has prepared for the first time ever a pyridine-containing LXA4 analogue in enantiomerically pure form. Biological evaluation determined that both epimers at the benzylic position suppress key cytokines known to be involved in inflammatory disease, with the... more...
Computational Organometallic Chemistry
Springer 2012; US$ 149.99Computational methods have become an indispensible tool for elucidating the mechanism of organometallic reactions. This snapshot of state-of-the-art computational studies provides an overview of the vast field of computational organometallic chemistry. Authors from Asia, Europe and the US have been selected to contribute a chapter on their specialist... more...
Total Synthesis of Plakortide E and Biomimetic Synthesis of Plakortone B
Springer 2012; US$ 99.99In his thesis, Xiaoyu Sun conducts the first total synthesis of all possible stereoisomers of plakortide E and also confirms the absolute configuration of natural plakortide E. Xiaoyu Sun subsequently converts Plakortide E methyl ester to plakortone B in a biomimetic conversion. Construction and functionalization of cyclic peroxides are notoriously... more...









