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The Quantal Theory of Immunity
World Scientific Publishing Company 2010; US$ 114.00This book explains how the immune system functions, namely, how individual cells of the immune system make the decision to respond or not to respond to foreign microbes and molecules, and how the critical molecules function to trigger the cellular reactions in an all-or-none (quantal) manner. To date, there has not been a complete description of the... more...
Antibody Expression and Production
Springer 2011; US$ 169.99Engineered antibodies currently represent over 30 per cent of biopharmaceuticals in clinical trials and their total worldwide sales continue to increase significantly. The importance of antibody applications is reflected in their increasing clinical and industrial applications as well as in the progression of established and emerging production strategies.... more...
Bispecific Antibodies
Springer 2011; US$ 169.99The concept of using bispecific antibodies for cancer therapy by retargeting immune effector cells was developed several years ago. Initial clinical studies were rather disappointing mainly due to low efficacy, severe side effects and the immunogenicity of the bispecific antibodies. The progress in antibody engineering finally led to the generation... more...
Lyme Disease
CABI 2011; US$ 160.00Providing the medical practitioner with a broad scientific understanding, this book discusses the causative organism, its requisite ecosystem, disease epidemiology, host-Borrelia interactions, diagnostic testing, clinical manifestations, therapeutic options, and long term prognosis. It explicitly reviews both the basic biology of the infection and... more...
Gene Vaccines
Springer 2011; US$ 169.99The induction of antigen-specific immune responses after in vivo transfection with expression plasmids has triggered a revolution of vaccine research. After a first hype, evoked by the fascinating options of this method, clinical studies did not reach the ambitious aims and a phase of disillusion ensued. It became obvious that Gene vaccines displayed... more...
Lecture Notes: Immunology
Wiley 2011; US$ 39.95This introductory text provides a student-friendly review of essential immunity and immunopathology topics. Key concepts are introduced in an incremental fashion to provide a thorough overview of the field. Closely tailored to the undergraduate immunology curriculum, Part 1 outlines basic immunology, while Part 2 covers more disease-related and clinical... more...
Neutrophils in Infectious Diseases
Bentham Science Publishers 2011; US$ 39.00Host defense to intracellular pathogens depends upon both innate and adaptive cell-mediated immune responses. Polymorphonuclear neutrophil leukocytes which belong to the innate immune system are the first cells that are recruited massively within hours of microbial infection. The importance of neutrophils in the development of an immune response is... more...
Regulation of Gastrointestinal Mucosal Growth
Morgan & Claypool Life Sciences 2011; US$ 40.00The mammalian gastrointestinal mucosa is a rapidly self-renewing tissue in the body, and its homeostasis is preserved through the strict regulation of epithelial cell proliferation, growth arrest, and apoptosis. The control of the growth of gastrointestinal mucosa is unique and, compared with most other tissue in the body, complex. Mucosal growth is... more...
Anticarbohydrate Antibodies
Springer 2011; US$ 169.99Many pathogens and aberrant malignant cells express unique carbohydrates on their surface representing attractive targets for vaccine design. Considerable progress has recently been made in the identification of novel carbohydrate based vaccines and a large number has reached clinical phase studies. The success of several licensed carbohydrate based... more...
