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The Edge of Evolutionby Michael J. Behe
Simon & Schuster 2007; US$ 12.99When Michael J. Behe's first book, Darwin's Black Box, was published in 1996, it launched the intelligent design movement. Critics howled, yet hundreds of thousands of readers -- and a growing number of scientists -- were intrigued by Behe's claim that Darwinism could not explain the complex machinery of the cell. Now, in his long-awaited follow-up, Behe presents far more than a challenge to Darwinism: He presents the evidence of the genetics revolution -- the first direct evidence of nature's mutational pathways -- to radically redefine the debate about Darwinism. How much of life does Darwin's theory explain? Most scientists believe it accounts for everything from the machinery of the cell to the history of life on earth. Darwin's... more...
Herbal Drugsby K.G. Ramawat
Springer 2009; US$ 319.00This reference work covers for the first time the herbal drugs used in ethnomedicine and validated on modern scientific basis. In depth information prepared by experts traces the evolution of herbal drugs with civilization and their use as antioxidants, anticancerous, chemopreventors, memory enhancers, neuroprotective, immunomodulator, anti-inflammatory, and in stroke, cardiovascular disorders, erectile dysfunction; also covering safety issues and toxic effects. Many of our modern medicine have come from traditional use of plants such as Curcuma, Ginkgo, and Ginseng. Therefore, information on herbal drugs, from ethnomedicine to modern use, has been arranged based on their involvement in various ailments. This book offers researchers working... more...
Energy and Lifeby John Wrigglesworth
CRC Press 1997; US$ 52.95Using worked examples and illustrations this text describes the application of thermodynamics to the primary processes of life, such as energy capture, metabolism and work. An invaluable resource for biochemistry, biology and microbiology students. more...
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CRC Press 1996; US$ 99.95Focuses on research procedures in toxicology, aiming to illustrate concepts and types of toxicity from a mechanistic point of view. Examples of chemical intoxicants are used to illustrate mechanisms in each stage of toxicity. more...
Patch Clampingby Areles Molleman
John Wiley & Sons, Ltd. 2003; US$ 149.95Patch clamping is a widely applied electrophysiological technique for the study of ion channels; membrane proteins that regulate the flow of ions across cellular membranes and therefore influence the physiology of all cells. Patch Clamping aims to cover the basic principles and practical applications of this important technique. Starting with a review of the history of patch clamping, the text then goes on to cover the basic principles, platforms, equipment and environmental control, and will also include coverage of preparation types, recording modes and analysis of results. * This book will explain the basic principles and practical application of patch clamp electrophysiology. * Written in a non-technical style to ensure its broad appeal... more...
LC/MS Applications in Drug Developmentby Mike S. Lee
John Wiley & Sons, Inc. 2003; US$ 154.00Breakthroughs in combinatorial chemistry and molecular biology, as well as an overall industry trend toward accelerated development, mean the rate of sample generation now far exceeds the rate of sample analysis in the pursuit of producing new and better pharmaceuticals. LC/MS is an analytical tool that helps the researcher identify the most promising sample early in the selection process, effectively creating a shortcut to finding new drugs. This book is the first to describe LC/MS applications within the context of drug development, including the discovery, preclinical, clinical, and manufacturing phases. In addition to the thorough technical analysis of this tool, LC/MS Applications in Drug Development provides perspective on the significant... more...
An Introduction to Computational Biochemistryby C. Stan Tsai
John Wiley & Sons, Inc. 2003; US$ 102.50This comprehensive text offers a solid introduction to the biochemical principles and skills required for any researcher applying computational tools to practical problems in biochemistry. Each chapter includes an introduction to the topic, a review of the biological concepts involved, a discussion of the programming and applications used, key references, and problem sets and answers. Providing detailed coverage of biochemical structures, enzyme reactions, metabolic simulation, genomic and proteomic analyses, and molecular modeling, this is the perfect resource for students and researchers in biochemistry, bioinformatics, bioengineering and computational science. more...
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CRC Press 1996; US$ 159.95Glutathione s-transferases (GSTs) constitute the most important enzymes protecting human and many other organisms from potentially toxic chemicals, including drugs and carcinogens. This book reviews scientific developments in research of this enzyme more...
Advances in Chemical Physics.by Richard A. Friesner
John Wiley & Sons, Inc. 2004; US$ 310.00Since the first attempts to model proteins on a computer began almost thirty years ago, our understanding of protein structure and dynamics has dramatically increased. Spectroscopic measurement techniques continue to improve in resolution and sensitivity, allowing a wealth of information to be obtained with regard to the kinetics of protein folding and unfolding, and complementing the detailed structural picture of the folded state. Concurrently, algorithms, software, and computational hardware have progressed to the point where both structural and kinetic problems may be studied with a fair degree of realism. Despite these advances, many major challenges remain in understanding protein folding at both the conceptual and practical levels. ... more...
Enzymesby Robert A. Copeland
John Wiley & Sons, Inc. 2004; US$ 174.00Fully updated and expanded-a solid foundation for understanding experimental enzymology. This practical, up-to-date survey is designed for a broad spectrum of biological and chemical scientists who are beginning to delve into modern enzymology. Enzymes, Second Edition explains the structural complexities of proteins and enzymes and the mechanisms by which enzymes perform their catalytic functions. The book provides illustrative examples from the contemporary literature to guide the reader through concepts and data analysis procedures. Clear, well-written descriptions simplify the complex mathematical treatment of enzyme kinetic data, and numerous citations at the end of each chapter enable the reader to access the primary literature and... more...
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