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  • Cardiac Adaptationsby Bohuslav Ostadal; Naranjan S. Dhalla

    Springer 2012; US$ 239.00

    This book summarizes present knowledge of different mechanisms involved in the development of positive and negative consequences of cardiac adaptation. Particular attention is paid to the still underestimated adaptive cardiac responses during development, to adaptation to the frequently occurring pressure and volume overload as well as to cardiac changes,... more...

  • Role of Proteases in Cellular Dysfunctionby Sajal Chakraborti; Naranjan S. Dhalla

    Springer 2013; US$ 239.00

    It is now well known that proteases are found everywhere, in viruses and bacteria as well as in all human, animal and plant cells, and play a role in a variety of biological functions ranging from digestion, fertilization, development to senescence and death. Under physiological conditions the ability of proteases is regulated by endogenous inhibitors.... more...

  • Proteases in Health and Diseaseby Sajal Chakraborti; Naranjan S. Dhalla

    Springer 2013; US$ 189.00

    In view of rapidly growing research in the deregulation of proteases and their impact in human health and diseases, this book will highlight existing and emerging research in this exciting area. In-depth critical state-of-the-art reviews will be written by established investigators on proteases dysfunctions associated with pathogenesis of different... more...

  • Diabetic Cardiomyopathyby Belma Turan; Naranjan S. Dhalla

    Springer 2014; US$ 209.00

    Diabetes has long been recognized as a disease of high blood sugar, and there has been a continuous search of the exact reason for its development and effective treatment. In 2005, the World Health Organization had estimated that more than 180 million people worldwide suffer from diabetes mellitus and indicated that this figure is likely to double... more...

  • Phospholipases in Health and Diseaseby Paramjit S Tappia; Naranjan S. Dhalla

    Springer 2014; US$ 209.00

    Phospholipases generate lipid signaling molecules through their hydrolytic action on phospholipids and are known to regulate function of a variety of cells under normal and diseased conditions. While several physiological, biochemical and molecular techniques have identified key players involved in different disease processes, phospholipases have also... more...

  • Genes and Cardiovascular Functionby Bohuslav Ostadal; Makoto Nagano; Naranjan S. Dhalla

    Springer 2011; US$ 219.00

    Rapid advances in molecular medicine have led to pronounced new developments in experimental and clinical cardiology. In the embrace of modern molecular biology and bridging the gap between the clinical and the genomic, cardiovascular medicine has seen major strides in the understanding of the molecular mechanisms that drive disease progression. The... more...

  • Molecular Defects in Cardiovascular Diseaseby Naranjan S. Dhalla; Makoto Nagano; Bohuslav Ostadal

    Springer Fachmedien 2011; US$ 219.00

    "Molecular Defects in Cardiovascular Disease" provides an in-depth discussion of the molecular mechanisms underlying the genesis of cardiovascular defects and the implications this has on current and emerging targeted therapeutics. Divided into three sections, this book covers the scientific foundations of our present understanding as well... more...

  • Cardiac Remodelingby Bodh I. Jugdutt; Naranjan S. Dhalla

    Springer 2013; US$ 239.00

    The main objective of Cardiac Remodeling: Molecular Mechanisms is to summarize the major research advances in molecular, biochemical and translational aspects of cardiac remodeling over the last 2 to 3 decades under one cover and touch on future directions. It provides a high profile and valuable publication resource on molecular mechanisms of cardiac... more...

  • Biochemical Basis and Therapeutic Implications of Angiogenesisby Jawahar L. Mehta; Naranjan S. Dhalla

    Springer 2013; US$ 239.00

    Angiogenesis is a highly complex phenomenon where new blood vessels are formed for the supply of oxygen and nutrients in different organs of the body.  It plays a critical role in both physiological processes such as growth and development as well as pathological processes including cancer and different types of tumors.  Angiogenesis is also... more...

  • Cardiac Energy Metabolism in Health and Diseaseby Ph.D. Gary D. Lopaschuk; Naranjan S. Dhalla

    Springer 2014; US$ 189.00

    The heart has a very high energy demand but very little energy reserves. In order to sustain contractile function, the heart has to continually produce a large amount of ATP.?The heart utilizes free fatty acids mainly and carbohydrates to some extent as substrates for making energy and any change in this energy supply can seriously compromise cardiac... more...

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