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  • Fluorescence In Situ Hybridization (FISH)by Thomas Liehr

    Springer 2008; US$ 189.99

    Provides an overview of the principles and the basic techniques of fluorescence in situ hybridization (FISH) and primed in situ hybridization (PRINS), which are used to study many aspects of genomic behavior and alterations. This work describes methods using various cell types and tissues as well as different organisms, such as mammalians. more...

  • Small Supernumerary Marker Chromosomes (sSMC)by Thomas Liehr

    Springer 2011; US$ 69.95

    Human beings normally have a total of 46 chromosomes, with each chromosome present twice, apart from the X and Y chromosomes in males. Some three million people worldwide, however, have 47 chromosomes: they have a small supernumerary marker chromosome (sSMC) in addition to the 46 normal ones. This sSMC can originate from any one of the 24 human chromosomes... more...

  • Benign & Pathological Chromosomal Imbalancesby Thomas Liehr

    Elsevier Science 2013; US$ 99.95

    Benign & Pathological Chromosomal Imbalances systematically clarifies the disease implications of cytogenetically visible copy number variants (CG-CNV) using cytogenetic assessment of heterochromatic or euchromatic DNA variants. While variants of several megabasepair can be present in the human genome without clinical consequence, visually distinguishing... more...

  • Uniparental Disomy (UPD) in Clinical Geneticsby Thomas Liehr; UNIQUE

    Springer 2014; US$ 79.99

    This book focus on genetic diagnostics for Uniparental Disomy (UPD), a chromosomal disorder defined by the exceptional presence of a chromosome pair derived from only one parent, which leads to a group of rare diseases in humans. First the molecular and cytogenetic background of UPD is described in detail; subsequently, all available information of... more...

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