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  • Proteases in the Brainby Uwe Lendeckel; Nigel M Hooper

    Springer US 2006; US$ 226.35

    In all organs of the body, proteases have critical roles to play both in normal development and functioning and in disease states. The brain is no exception to this, with proteases having emerging roles in synaptic plasticity, memory, neurodegenerative disorders such as Alzheimer?s, Parkinson?s and prion diseases, ischemia and traumatic brain injury,... more...

  • The ADAM Family of Proteasesby Nigel M Hooper; Uwe Lendeckel

    Springer US 2006; US$ 218.75

    The ADAM Family of Proteases provides the first comprehensive review of the roles of ADAMs and the related ADAMTS proteases in biology and disease. Although a few members of the ADAM (a disintegrin and metalloprotease) family have been known for some time, it is only in recent years through advances in genome sequencing that the large size of this... more...

  • Proteases in Gastrointestinal Tissuesby Uwe Lendeckel; Nigel M. Hooper

    Springer Netherlands 2006; US$ 218.75

    This, the fifth volume in the Proteases in Biology and Disease series, is devoted to Proteases in Gastrointestinal Tissues. Of course, proteases play an important role in the digestion and utilization of ingested proteins, but besides that they elicit a wide range of physiological and pathological effects. Proteases have been recognized as essential... more...

  • Intramembrane-Cleaving Proteases (I-CLiPs)by Nigel M. Hooper; Uwe Lendeckel

    Springer Netherlands 2007; US$ 153.89

    Authors Nigel M. Hooper and Otto von Guericke, world leaders in protease research, have written the first book that focuses on recent data stemming from the structural determination of intramembrane-cleaving proteases (I-CLiPs). You get the latest findings concerning the various roles that these proteases play in biology and in the course of diseases... more...

  • Viral Proteases and Antiviral Protease Inhibitor Therapyby Uwe Lendeckel; Nigel M. Hooper

    Springer Netherlands 2009; US$ 208.85

    The eighth volume in the Proteases in Biology and Disease series, this text focuses on viral proteases, crucial prerequisites for viral entry into cells, and viral replication. It discusses viral proteases of key pathogenic viruses, such as AIDS and SARS. more...

  • Aminopeptidases in Biology and Diseaseby Nigel M. Hooper; Uwe Lendeckel

    Springer US 2012; US$ 98.92

    Aminopeptidases in Biology and Disease provides a comprehensive review of the emerging role of aminopeptidases in a range of biological processes and disease situations. Processes as diverse as angiogenesis, antigen presentation, neuropeptide and hormone processing, pregnancy and reproduction, protein turnover, memory, inflammation, tumour growth,... more...

  • Proteases in Tissue Remodelling of Lung and Heartby Uwe Lendeckel; Nigel M. Hooper

    Springer US 2012; US$ 142.89

    Proteases in Tissue Remodelling of Lung and Heart is unique for its comprehensive presentation of protease function in lung and heart under both physiological conditions and major diseases manifesting in these two organs. The individual chapters have been written by leaders in the field who paid much attention to outline in great detail the role... more...

  • Dipeptidyl Aminopeptidasesby Uwe Lendeckel; Dirk Reinhold; Ute Bank

    Springer US 2006; US$ 240.74

    Dipeptidyl Aminopeptidases exert a potent modulatory role at an interface between immune mechanisms, metabolic responses, and neuroendocrine pathways. Experimental models and clinical studies addressing the role of these enzymes and the effect of specific inhibitors pave the way to novel therapeutic concepts in immunology, rheumatology, oncology,... more...

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