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  • Novartis Foundation Symposium 289by Novartis Foundation

    Wiley 2008; US$ 219.00

    The recent identification of susceptibility genes for schizophrenia, depression and learning and memory dysfunction suggest that psychiatric disorders may be influenced by a small number of genes with multiple actions. This is the first book to investigate the role of growth factors in these disorders, which should provide clues to the underlying biochemical... more...

  • Transport and Trafficking in the Malaria-Infected Erythrocyteby Novartis Foundation

    Wiley 2008; US$ 160.00

    There is an urgent need to uncover new therapies that will protect against malaria, as the parasite becomes increasingly resistant to available drugs and this book offers insights into three interrelated aspects of the malaria-infected erythrocyte: * The transport of solutes into and out of the infected cell and the use of specific trafficking pathways... more...

  • Immunological Toleranceby Novartis Foundation

    Wiley 2008; US$ 160.00

    This book brings together material on all aspects of immunological tolerance. Basic mechanisms of tolerance are examined in detail, including mechanisms of peripheral T cell tolerance, molecular and genetic mechanisms for maintaining self tolerance, partial T cell activation, and the role of apoptosis in tolerance. Careful consideration is also given... more...

  • Bacterial Responses to pHby Novartis Foundation

    Wiley 2008; US$ 160.00

    Microbial responses to acidic and alkaline pH are important in many areas of bacteriology. For example, the mechanisms of resistance to acidic pH are important in the understanding of the passage of human pathogens through the acid of the stomach; and an understanding of microbial degradation of alkaline industrial waste is important for the environment.... more...

  • Rhodopsins and Phototransductionby Novartis Foundation

    Wiley 2008; US$ 160.00

    Brings together key new results of interdisciplinary collaborations among various research fields on rhodopsin including the photoreceptive mechanism of rhodopsins, the molecular mechanism of the visual transduction process, visual processes in the retina and other transduction processes in the retina and brain. The structures of the rhodopsin molecule... more...

  • Rice Biotechnologyby Novartis Foundation

    Wiley 2008; US$ 219.00

    Rice is the most important food crop for half the world's population. Over the last three decades, the imporvement in human nutrition and health in Asia has largely been attributable to a relatively stable and affordable rice supply. The challenge to produce enough rice for the future, however, remains daunting, as the current rate of population growth... more...

  • The Biology of Extracellular Molecular Chaperonesby Novartis Foundation

    Wiley 2008; US$ 219.00

    The heat shock, or cell stress, response was first identified in the polytene chromosomes of Drosophila . This was later related to the appearance of novel proteins within stressed cells, and the key signal stimulating this appearance was identified as the presence of unfolded proteins within the cell. It is now known that this is a key mechanism... more...

  • Fatty Acid and Lipotoxicity in Obesity and Diabetesby Novartis Foundation

    Wiley 2008; US$ 219.00

    The potential lipotoxic effect of accumulation of fatty acids in non-adipose tissues is thought to be a major component in the development of insulin resistance. Chronic exposure to high concentrations of free fatty acids in the blood affects pancreatic β cell function, insulin secretion and lipid synthesis in the liver, and storage in adipose... more...

  • Nuclear Organization in Development and Diseaseby Novartis Foundation

    Wiley 2006; US$ 219.00

    This book draws together contributions from cell and developmental biologists, structural biologists, geneticists and clinical scientists aimed at a better understanding of the cellular and molecular basis of these diseases. Topics include: How nuclear structure and location within a nucleus affect gene expression Chromatin organization and cell... more...

  • Epithelial Anion Transport in Health and Diseaseby Novartis Foundation

    Wiley 2006; US$ 219.00

    Cl- absorption and HCO3- secretion are intimately associated processes vital to epithelial function, itself a key physiological activity. Until recently the transporters responsible remained obscure, but a breakthrough occurred with the discovery of the SLC26 transporters family. It is now clear that the SLC26 transporters have broad physiological... more...