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  • Mucus Hypersecretion in Respiratory Diseaseby Novartis Foundation

    Wiley 2003; US$ 212.00

    A number of chronic respiratory diseases including chronic bronchitis, asthma, cystic fibrosis and bronchiectasis are characterized by mucus hypersecretion. Following damage to the airway epithelium, a repair process of dedifferentiation, regenerative proliferation and redifferentiation takes place that is invariably accompanied by mucus hypersecretion... more...

  • 'In Silico' Simulation of Biological Processesby Novartis Foundation

    Wiley 2003; US$ 212.00

    Over recent decades vast amounts of biological data have been accumulated. However, it is becoming increasingly difficult to apply traditional theoretical methods to the formulation of coherent pictures of cell and organ function because it is no longer possible for a human theorist to integrate all of the available information. Instead, computer technologies... more...

  • Neuronal and Cognitive Effects of Oestrogensby Novartis Foundation

    Wiley 2003; US$ 212.00

    Although normally thought of as a sex hormone, recent research has highlighted the numerous and significant effects that oestrogen has on the CNS, extending far beyond its important reproductive role. It has been shown that oestrogen acts as a neural growth factor with important influences on the survival, plasticity, regeneration and ageing of the... more...

  • Neural Transplantation in Neurodegenerative Diseaseby Novartis Foundation

    Wiley 2003; US$ 212.00

    The field of neural transplantation is at a crucial stage, with  important clinical trials on transplantation in patients with Parkinson's disease nearing completion and novel, alternative approaches to fetal transplantation being developed. This timely book brings together leading neuroscientists, clinicians, and cell and developmental biologists... more...

  • The Nature of Intelligenceby Novartis Foundation

    Wiley 2003; US$ 212.00

    Evolutionary psychology and behavioural genetics are two successful and important fields in the study of human behaviour, but practitioners in these subjects have different conceptions of the nature of human intelligence. Evolutionary psychologists dispute the existence of general intelligence and emphasise the differences among species.... more...

  • Autismby Novartis Foundation

    Wiley 2005; US$ 212.00

    This book draws together contributions from some of the leading investigators in the field of autism to consider specific problem areas in current research. Each contributor brings expertise from a different field, providing a balanced view of the whole spectrum of study of this disorder. It covers four main areas: * Twin and family studies indicate... more...

  • Cancer and Inflammationby Novartis Foundation

    Wiley 2004; US$ 212.00

    Chronic inflammation predisposes to some forms of cancer and the host response to malignant disease shows several parallels with inflammation and wound healing. The cells involved in inflammation are detected in a range of common cancers, together with the inflammatory cytokines and members of the chemokine ligand/receptor systems. Neutralization... more...

  • Reversible Protein Acetylationby Novartis Foundation

    Wiley 2004; US$ 212.00

    A comprehensive review of recent work on chromatin and non-histone proteins, this book arises from the interactions of a multidisciplinary group of scientists involved in the study of acetylation. This area of research opens up new and exciting possibilities for drug design, and so the final chapters in the book examine some of the potential applications... more...

  • Mammalian TRP Channels as Molecular Targetsby Novartis Foundation

    Wiley 2004; US$ 212.00

    This book brings together contributions from key investigators in the area of Transient Receptor Potential (TRP) channel structure and function.  It covers the structure, function and regulation of mammalian TRP channels and mechanisms of signal transduction.  The discussions indicate research that would improve understanding of the role... more...

  • Generation and Effector Functions of Regulatory Lymphocytesby Novartis Foundation

    Wiley 2004; US$ 212.00

    Over the last several years, immunologists have re-discovered the importance of regulatory lymphocytes, formerly termed 'suppressor cells'. Many recent reports have documented their existence, effector functions and potential therapeutic benefits in autoimmunity and transplantation. However, even though modern techniques have allowed us to get a much... more...