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  • Mathematical Modelling of Chromosome Replication and Replicative Stressby Jens Karschau

    Springer 2014; US$ 129.00

    DNA replication is arguably the most crucial process at work in living cells. It is the mechanism by which organisms pass their genetic information from one generation to the next and life on Earth would be unthinkable without it. Despite the discovery of DNA structure in the 1950s, the mechanism of its replication remains rather elusive.This work... more...

  • Modelling the Short QT Syndrome Gene Mutationsby Ismail Adeniran

    Springer 2014; US$ 179.00

    The Short QT Syndrome (SQTS) is characterized by abbreviated QT intervals on the electrocardiogram, increased risk of cardiac arrhythmias and sudden death. Although several gene mutations have been identified in SQT patients, the role of these mutations in promoting arrhythmogenesis is still not completely understood. Consequently, this thesis employs... more...

  • Biomolecular Feedback Systemsby Domitilla Del Vecchio; Richard M. Murray

    Princeton University Press 2014; US$ 85.00

    This book provides an accessible introduction to the principles and tools for modeling, analyzing, and synthesizing biomolecular systems. It begins with modeling tools such as reaction-rate equations, reduced-order models, stochastic models, and specific models of important core processes. It then describes in detail the control and dynamical systems... more...

  • Counting Molecules Within Cellsby Valerie Coffman; I-Ju Lee; Jian-Qiu Wu

    Biota Publishing 2014; US$ 60.00

    A fundamental component of quantitative cell biology is the ability to count molecules within cells. The numbers of molecules and stoichiometries are the basis for structural models of protein complexes and simulations of biological processes. A variety of methods exist for in vivo quantifications, but the focus of this volume is mainly on fluorescence... more...

  • Fundamentals of Biophysicsby Andrey B. Rubin

    Wiley 2014; US$ 195.00

    Biophysics is a science that comprises theoretical plotting and models based on contemporary physicochemical conceptions. They mirror physical specificity of the molecular organization and elementary processes in living organisms, which in their turn form the molecular basis of biological phenomena. Presentation of a complete course in biophysics... more...

  • Interleukin-10 in Health and Diseaseby Simon Fillatreau; Anne O'Garra

    Springer 2014; US$ 189.00

    This volume provides a set of reviews dedicated to the biology of Interleukin (IL)-10. It includes chapters on its importance for maintaining immune homeostasis in humans, its role in intestinal immunity and its functions during viral and bacterial infections. In addition, it presents reviews on the mechanisms linking innate microbial recognition to... more...

  • Anticancer Genesby Stefan Grimm

    Springer 2014; US$ 189.00

    This book discusses the emergence of a new class of genes with a specific anticancer activity. These genes, recently defined as ?Anticancer Genes?, are reviewed in individual chapters on their mode of action, the specific cell death signals they induce, and the status of attempts to translate them into clinical application. Anticancer Genes provides... more...

  • Nucleic Acids in the Gas Phaseby Valérie Gabelica

    Springer 2014; US$ 129.00

    This book gives physical chemists a broader view of potential biological applications of their techniques for the study of nucleic acids in the gas phase. It provides organic chemists, biophysicists, and pharmacologists with an introduction to new techniques they can use to find the answers to yet unsolved questions. Laboratory sciences have bloomed... more...

  • Mechanics of Biological Systems and Materials, Volume 7by Francois Barthelat; Chad Korach; Pablo Zavattieri; Barton C. Prorok; K. Jane Grande-Allen

    Springer 2014; US$ 199.00

    Mechanics of Biological Systems and Materials, Volume 7: Proceedings of the 2014 Annual Conference on Experimental and Applied Mechanics, the seventh volume of eight from the Conference, brings together contributions to this important area of research and engineering.? The collection presents early findings and case studies on a wide range of areas,... more...

  • Microbial Biochemistryby Georges N. Cohen

    Springer 2014; US$ 209.00

    Microbial physiology, biochemistry and genetics allowed the formulation of concepts that turned out to be important in the study of higher organisms. In the first section, the principles of bacterial growth are given, as well as the description of the different layers that enclose the bacterial cytoplasm, and their role in obtaining nutrients from... more...