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Biochemistry

Most popular at the top

  • Adenosine Deaminases Acting on RNA (ADARs) and A-to-I Editingby Charles E. Samuel

    Springer 2011; US$ 219.00

    The objective of this "CTMI" volume is to provide readers with a foundation for understanding what ADARs are and how they act to affect gene expression and function. It is becoming increasingly apparent that ADARs may possess roles not only as enzymes that deaminate adenosine to produce inosine in RNA substrates with double-stranded character,... more...

  • Microbial Degradation of Xenobioticsby Shree Nath Singh

    Springer 2011; US$ 209.00

    Our interest in the microbial biodegradation of xenobiotics has increased many folds in recent years to find out sustainable ways for environmental cleanup. Bioremediation and biotransformation processes harness the naturally occurring ability of microbes to degrade, transform or accumulate a wide range of organic pollutants. Major methodological breakthroughs... more...

  • Formation and Cooperative Behaviour of Protein Complexes on the Cell Membraneby Ksenia Guseva

    Springer 2011; US$ 129.00

    With the aim of providing a deeper insight into possible mechanisms of biological self-organization, this thesis presents new approaches to describe the process of self-assembly and the impact of spatial organization on the function of membrane proteins, from a statistical physics point of view. It focuses on three important scenarios: the assembly... more...

  • Heteroaromatic Lipoxin A4 Analoguesby Colm Duffy

    Springer 2012; US$ 129.00

    In this thesis Colm Duffy reviews the chemistry and biology of stable lipoxin analogues. Colm has prepared for the first time ever a pyridine-containing LXA4 analogue in enantiomerically pure form. Biological evaluation determined that both epimers at the benzylic position suppress key cytokines known to be involved in inflammatory disease, with the... more...

  • Computational Organometallic Chemistryby Olaf Wiest; Yundong Wu

    Springer 2012; US$ 189.00

    Computational methods have become an indispensible tool for elucidating the mechanism of organometallic reactions. This snapshot of state-of-the-art computational studies provides an overview of the vast field of computational organometallic chemistry. Authors from Asia, Europe and the US have been selected to contribute a chapter on their specialist... more...

  • Total Synthesis of Plakortide E and Biomimetic Synthesis of Plakortone Bby Xiao-Yu Sun

    Springer 2012; US$ 129.00

    In his thesis, Xiaoyu Sun conducts the first total synthesis of all possible stereoisomers of plakortide E and also confirms the absolute configuration of natural plakortide E. Xiaoyu Sun subsequently converts Plakortide E methyl ester to plakortone B in a biomimetic conversion. Construction and functionalization of cyclic peroxides are notoriously... more...

  • Field-Flow Fractionation in Biopolymer Analysisby S. Kim R. Williams; Karin D. Caldwell

    Springer 2012; US$ 189.00

    This is a timely collection of important biomedical applications for a set of separation/characterization techniques that are rapidly gaining popularity due to their wide dynamic range, high resolution, and ability to function in most commonly used solvent systems. Importantly, the field-flow fractionation (FFF) technique has recently emerged as a... more...

  • DNA Topoisomerases and Cancerby Yves Pommier

    Springer 2011; US$ 249.00

    DNA topoisomerases represent an essential family of DNA processing enzymes and a large number of topoisomerase inhibitors are used clinically for the treatment of various human cancers. Novels drugs are in clinical development both against type I and type II topoisomerases. The book will include basic biochemical and structural reviews for the cancer-relevant... more...

  • RNA Infrastructure and Networksby Lesley J. Collins

    Springer 2011; US$ 219.00

    RNAs form complexes with proteins and other RNAs. The RNA-infrastructure represents the spatiotemporal interaction of these proteins and RNAs in a cell-wide network. "RNA Infrastructure and Networks" brings together these ideas to illustrate the scope of RNA-based biology, and how connecting RNA mechanisms is a powerful tool to investigate... more...

  • Seleniumby Dolph L. Hatfield; Marla J. Berry; Vadim N. Gladyshev

    Springer 2011; US$ 179.00

    Many health benefits have been attributed to selenium that include preventing various forms of cancer (e.g., colon cancer, prostate cancer, lung cancer and liver cancer), heart disease and other cardiovascular and muscle disorders, inhibiting viral expression, delaying the progression of acquired immunodeficiency syndrome (AIDS) in human immunodeficiency... more...