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- CRC Press 2011; US$ 100.95
With new statistical and scientific issues arising in adaptive clinical trial design, including the U.S. FDA?s recent draft guidance, a new edition of one of the first books on the topic is needed. Adaptive Design Methods in Clinical Trials, Second Edition reflects recent developments and regulatory positions on the use of adaptive designs in clinical... more...
- CRC Press 2014; US$ 60.00
Get Up to Speed on Many Types of Adaptive Designs Since the publication of the first edition, there have been remarkable advances in the methodology and application of adaptive trials. Incorporating many of these new developments, Adaptive Design Theory and Implementation Using SAS and R, Second Edition offers a detailed framework to understand... more...
- Springer International Publishing 2016; US$ 64.50
This book presents methods for investigating whether relationships are linear or nonlinear and for adaptively fitting appropriate models when they are nonlinear. Data analysts will learn how to incorporate nonlinearity in one or more predictor variables into regression models for different types of outcome variables. Such nonlinear dependence is often... more...
- Springer Berlin Heidelberg 2012; US$ 37.62
This book aims to provide an overview of some adaptive techniques used in estimating parameters for finite populations where the sampling at any stage depends on the sampling information obtained to date. The sample adapts to new information as it comes in. These methods are especially used for sparse and clustered populations. Written by two acknowledged... more...
- CRC Press 2016; US$ 99.95
Adaptive clinical trial designs, unlike traditional fixed clinical trial designs, enable modification of studies in response to the data generated in the course of the trial. This often results in studies that are substantially faster, more efficient, and more powerful. Recent developments in web-based real-time data entry and advances in statistical... more...
- Springer Milan 2012; US$ 139.76
This book presents a collection of concrete applications to situations detailing the problem areas of making difficult decisions in the health care field. It examines the methodology employed in making these decisions, the implementation and results. more...
- World Scientific Publishing Company 2015; US$ 160.00 US$ 145.60
The book aims to provide both comprehensive reviews of the classical methods and an introduction to new developments in medical statistics. The topics range from meta analysis, clinical trial design, causal inference, personalized medicine to machine learning and next generation sequence analysis. Since the publication of the first edition, there have... more...
- World Scientific Publishing Company 2003; US$ 118.00 US$ 107.38
This book presents new and powerful advanced statistical methods that have been used in modern medicine, drug development, and epidemiology. Some of these methods were initially developed for tackling medical problems.All 29 chapters are self-contained. Each chapter represents the new development and future research topics for a medical or statistical... more...
- Springer US 2006; US$ 310.72
Advanced Methods of Pharmacokinetic and Pharmocodynamic Systems Analysis Volume 3 is vital to professionals and academicians working in drug development and bioengineering. Both basic and clinical scientists will benefit from this work. This book contains chapters by leading researchers in pharmacokinetic/pharmacodynamic modeling and will be of interest... more...