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Genetics

  • Fibrous Proteins: Structures and Mechanismsby David A.D. Parry; John M. Squire

    Springer International Publishing 2017; US$ 182.76

    This book provides the readers with an up-to-date review of the design, structure and function of a representative selection of fibrous proteins in both health and disease. The importance of the ?-helical coiled coil, a conformational motif based on the heptad repeat in the amino acid sequence of all ?-fibrous proteins (and parts of some globular... more...

  • Current Strategies in Cancer Gene Therapyby Wolfgang Walther

    Springer International Publishing 2017; US$ 129.01

    This book describes important developments and emerging trends in experimental and clinical cancer gene therapy. It reflects the tremendous advances made over recent years with respect to immunogenes, suicide genes and gene correction therapies, as well as in gene suppression and miRNA therapies. Many of the described strategies focus on the generation... more...

  • Parental Responsibility in the Context of Neuroscience and Geneticsby Kristien Hens; Daniela Cutas; Dorothee Horstkötter

    Springer International Publishing 2017; US$ 93.53

    Should parents aim to make their children as normal as possible to increase their chances to ?fit in?? Are neurological and mental health conditions a part of children?s identity and if so, should parents aim to remove or treat these? Should they aim to instill self-control in their children? Should prospective parents take steps to insure that,... more...

  • Human Retrotransposons in Health and Diseaseby Gael Cristofari

    Springer International Publishing 2017; US$ 161.26

    This unique book explores the role of retrotransposons in human health and disease. The ability of retrotransposons to affect the structure of human genes is recognized since the late 80?s. However, the advances of deep-sequencing technologies have shed new light on the extent of retrotransposon-mediated genome variations. These progresses... more...

  • JIMD Reports, Volume 31by Eva Morava; Matthias Baumgartner; Marc Patterson; Shamima Rahman; Johannes Zschocke; Verena Peters

    Springer Berlin Heidelberg 2017; US$ 96.75

    JIMD Reports publishes case and short research reports in the area of inherited metabolic disorders. Case reports highlight some unusual or previously unrecorded feature relevant to the disorder, or serve as an important reminder of clinical or biochemical features of a Mendelian disorder. more...

  • Identifying Novel Inborn Errors of the Immune Systemby Elisabeth Salzer

    Springer Fachmedien Wiesbaden 2017; US$ 35.47

    In her study Elisabeth Salzer describes three novel monogenic diseases. For CD27 deficiency Elisabeth Salzer describes a large cohort of patients. Although all patients shared the same causative missense mutation, they displayed diverse clinical presentations. In another patient she was able to identify a mutation in PRKCD resulting in a primary... more...

  • Translating Epigenetics to the Clinicby Jeffrey Laurence

    Elsevier Science 2016; US$ 99.95

    Translating Epigenetics to the Clinic reviews current methodological tools and experimental approaches used by leading translational researchers seeking to use epigenetics as a clinical model. It organizes epigenetics into disease treatment areas with a major focus on oncology, and with much coverage of pervasive treatment categories such as diabetes,... more...

  • The Oxford Handbook of Reproductive Ethicsby Leslie Francis

    Oxford University Press 2016; US$ 149.99

    Intimate and medicalized, natural and technological, reproduction poses some of the most challenging ethical dilemmas of our time. This volume brings together scholars from multiple perspectives to address both traditional and novel questions about the rights and responsibilities of human reproducers, their caregivers, and the societies in which they... more...

  • Therapeutic Applications of Adenovirusesby Philip Ng; Nicola Brunetti-Pierri

    CRC Press 2016; US$ 149.95

    Adenoviruses are double stranded DNA viruses that have been used to study the process of DNA replication. Studies of the mode of action of adenovirally produced tumors in rodents led to the discovery of tumour supressor genes. The adenoviral vector is now the most used vector in clinical gene therapy especially for some kinds of cancers. The chapters... more...

  • Biomarkers and Mental Illnessby Paul C. Guest

    Springer International Publishing 2016; US$ 18.27

    Employing accessible language throughout, this book covers the history of psychiatric research, the current state-of-the art in psychiatric practice, the physiological systems affected by psychiatric illnesses, the whole-body nature of these diseases and the impact that this aspect has on emerging biomarker discoveries.  Further, it provides... more...