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Research

  • Brain Neurotraumaby Firas H. Kobeissy

    Taylor and Francis 2015; US$ 229.95

    Every year, an estimated 1.7 million Americans sustain brain injury. Long-term disabilities impact nearly half of moderate brain injury survivors and nearly 50,000 of these cases result in death. Over the last decade, the field of neurotrauma has witnessed significant advances, especially at the molecular, cellular, and behavioral levels. This progress... more...

  • Bulletin of WHO Vol. 93 No. 02 2015by World Health Organization

    World Health Organization 2015; US$ 36.00

    The Bulletin of the World Health Organization is an international journal of public health with a special focus on developing countries. Since it was first published in 1948 the Bulletin has become one of the world's leading public health journals. As the flagship periodical of the World Health Organization (WHO) the Bulletin draws on WHO experts... more...

  • Tumor Cell Metabolismby Sybille Mazurek; Maria Shoshan

    Springer Vienna 2015; US$ 0.00

    The four sections of this book cover cell and molecular biology of tumor metabolism, metabolites, tumor microenvironment, diagnostics and epigenetics. Written by international experts, it provides a thorough insight into and understanding of tumor cell metabolism and its role in tumor biology. The book is intended for scientists in cancer cell and... more...

  • Individualized Medicineby Tobias Fischer; Martin Langanke; Paul Marschall; Susanne Michl

    Springer International Publishing 2015; US$ 0.00

    In 2009 the University Medicine Greifswald launched the ?Greifswald Approach to Individualized Medicine? (GANI_MED) to implement biomarker-based individualized diagnostic and therapeutic strategies in clinical settings. Individualized Medicine (IM) has led not only to controversies about its potentials, but also about its societal, ethical and health... more...

  • Sample Size Calculations for Clustered and Longitudinal Outcomes in Clinical Researchby Chul Ahn; Moonseoung Heo; Song Zhang

    CRC Press 2015; US$ 89.95

    Accurate sample size calculation ensures that clinical studies have adequate power to detect clinically meaningful effects. This results in the efficient use of resources and avoids exposing a disproportionate number of patients to experimental treatments caused by an overpowered study. Sample Size Calculations for Clustered and Longitudinal Outcomes... more...

  • Quantitative Evaluation of Safety in Drug Developmentby Qi Jiang; H. Amy Xia

    CRC Press 2015; US$ 99.95

    State-of-the-Art Methods for Drug Safety Assessment Responding to the increased scrutiny of drug safety in recent years, Quantitative Evaluation of Safety in Drug Development: Design, Analysis and Reporting explains design, monitoring, analysis, and reporting issues for both clinical trials and observational studies in biopharmaceutical product... more...

  • Noninferiority Testing in Clinical Trialsby Tie-Hua Ng

    CRC Press 2015; US$ 79.95

    Take Your NI Trial to the Next Level Reflecting the vast research on noninferiority (NI) designs from the past 15 years, Noninferiority Testing in Clinical Trials: Issues and Challenges explains how to choose the NI margin as a small fraction of the therapeutic effect of the active control in a clinical trial. Requiring no prior knowledge... more...

  • Clinical Trial Biostatistics and Biopharmaceutical Applicationsby Walter R. Young; Ding-Geng (Din) Chen

    CRC Press 2015; US$ 119.95

    Since 1945, "The Annual Deming Conference on Applied Statistics" has been an important event in the statistics profession. In Clinical Trial Biostatistics and Biopharmaceutical Applications , prominent speakers from past Deming conferences present novel biostatistical methodologies in clinical trials as well as up-to-date biostatistical applications... more...

  • Statistical Methods in Drug Combination Studiesby Wei Zhao; Harry Yang

    CRC Press 2015; US$ 99.95

    The growing interest in using combination drugs to treat various complex diseases has spawned the development of many novel statistical methodologies. The theoretical development, coupled with advances in statistical computing, makes it possible to apply these emerging statistical methods in in vitro and in vivo drug combination assessments. However,... more...

  • Clinical and Statistical Considerations in Personalized Medicineby Claudio Carini; Sandeep M Menon; Mark Chang

    CRC Press 2015; US$ 89.95

    The Future of Clinical Research and Health Care: From Empirical to Precision Medicine Clinical and Statistical Considerations in Personalized Medicine explores recent advances related to biomarkers and their translation into clinical development. Leading clinicians, biostatisticians, regulators, commercial professionals, and researchers address... more...