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- Springer Berlin Heidelberg 2005; US$ 259.00
Natural Killer (NK) cells are large granular lymphocytes of the innate immune system. They are widespread throughout the body, being present in both lymphoid organs and non-lymphoid peripheral tissues. NK cells are involved in direct innate immune reactions against viruses, bacteria, parasites and other triggers of pathology, such as malignant transformation,... more...
- Birkhäuser Basel 2006; US$ 109.00
Georges Köhler was one of the most prominent German scientists of recent history. In 1984, at an age of 38, he received the Nobel Prize in Physiology or Medicine, together with N.K. Jerne and C. Milstein, for inventing the technique for generating monoclonal antibodies. This method and its subsequent applications had an enormous impact on basic research,... more...
- Birkhäuser Basel 2006; US$ 239.00
Over the last decade, the advent of biologic agents has greatly revolutionized therapeutic medicine in the management of chronic inflammatory diseases, such as rheumatoid arthritis, Crohn?s disease, and psoriasis. Elucidation of the complex web of cytokine network and the roles of these cytokines in the pat- genesis of inflammatory disorders provided... more...
- Wiley 2007; US$ 180.00 US$ 156.00
The authoritative reference on recent developments in vaccinology New technologies, including recombinant protein and DNA, have sparked phenomenal progress in vaccine development and delivery systems. This unique resource brings scientists up to date on recent advances and provides the information they need to select candidate adjuvants. With chapters... more...
- Springer Berlin Heidelberg 2006; US$ 259.00
TheBlymphocytelineagerepresentsaleadingsystemforexploring- lecularmechanismsthatunderliecellfatespecification,differentiationand cellular activation. In the past five years major advances have been achievedintheanalysisofearlyBcelldevelopment,AIDdependentclass switchrecombinationaswellassomatichypermutationandBlimp-1re- latedplasmacelldifferentiation.... more...
- Springer Berlin Heidelberg 2006; US$ 289.00
The vertebrate immune system defends the organism against invading pathogens while at the same time being self-tolerant to the body?s own constituentsthuspreservingitsintegrity. Multiplemechanismsactinconcert to ensure self-tolerance. During intrathymic development, the nascent T cell repertoire is purged from autoreactive T cells via negative selection,... more...
- Elsevier Science 2000; US$ 315.00
Of the two disciplines in parallel development for two decades, tumor immunology and transplantation immunology, the latter has thrived and has led to some of the most critical discoveries in immunobiology. The former continues to thwart both scientists and clinicians alike. The goal of immunologists in modern day research is to develop a simple and... more...
- Elsevier Science 1997; US$ 435.00
This is the most comprehensive review of the idiotypic network available. All the current knowledge of idiotypes of the various antibodies is incorporated in this volume. The pathogenic role of idiotypes in autoimmunity and cancer is reviewed in depth. The therapeutic part focusses on harnessing anti-idiotypes for treating autoimmunological disorders,... more...
- Springer US 2007; US$ 229.00
Toll Receptors and the Renaissance of Innate Immunity Elizabeth H. Bassett and Tina Rich Overview n the last few pages of Immunology: The Science of Self-Nonself Discrimination Jan Klein ponders on what he would study if he were to start over in the lab. ^ Dismissing the I antibody, MHC, the T-cell and parasitology, he considers instead the phylogeny... more...