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Most popular at the top

  • Köhler's Inventionby Klaus Eichmann

    Birkhäuser Basel 2006; US$ 76.02

    Georges Köhler was one of the most prominent German scientists of recent history. In 1984, at an age of 38, he received the Nobel Prize in Physiology or Medicine, together with N.K. Jerne and C. Milstein, for inventing the technique for generating monoclonal antibodies. This method and its subsequent applications had an enormous impact on basic research,... more...

  • TNF-alpha Inhibitorsby Jeffrey M. Weinberg; Robin Buchholz

    Birkhäuser Basel 2006; US$ 162.91

    Over the last decade, the advent of biologic agents has greatly revolutionized therapeutic medicine in the management of chronic inflammatory diseases, such as rheumatoid arthritis, Crohn?s disease, and psoriasis. Elucidation of the complex web of cytokine network and the roles of these cytokines in the pat- genesis of inflammatory disorders provided... more...

  • Molecular Analysis of B Lymphocyte Development and Activationby Harinder Singh; Rudolf Grosschedl

    Springer Berlin Heidelberg 2006; US$ 216.14

    TheBlymphocytelineagerepresentsaleadingsystemforexploring- lecularmechanismsthatunderliecellfatespecification,differentiationand cellular activation. In the past five years major advances have been achievedintheanalysisofearlyBcelldevelopment,AIDdependentclass switchrecombinationaswellassomatichypermutationandBlimp-1re- latedplasmacelldifferentiation.... more...

  • CD4+CD25+ Regulatory T Cells: Origin, Function and Therapeutic Potentialby B. Kyewski; Elisabeth Suri-Payer

    Springer Berlin Heidelberg 2006; US$ 237.86

    The vertebrate immune system defends the organism against invading pathogens while at the same time being self-tolerant to the body?s own constituentsthuspreservingitsintegrity. Multiplemechanismsactinconcert to ensure self-tolerance. During intrathymic development, the nascent T cell repertoire is purged from autoreactive T cells via negative selection,... more...

  • Cytokinesby C. Bondy; D. LeRoith

    Elsevier Science 1997; US$ 119.00

    Progress in molecular technology in recent years has caused an amazing growth of information about intercellular peptide messengers and their receptors. The number of characterized interleukins for example numbered just three six years ago and now there are at least 16. In addition, the number of described neutrophic peptides is around 30 and the... more...

  • Idiotypes in Medicineby R. C. Kennedy; S. Ferrone; Yehuda Shoenfeld

    Elsevier Science 1997; US$ 435.00

    This is the most comprehensive review of the idiotypic network available. All the current knowledge of idiotypes of the various antibodies is incorporated in this volume. The pathogenic role of idiotypes in autoimmunity and cancer is reviewed in depth. The therapeutic part focusses on harnessing anti-idiotypes for treating autoimmunological disorders,... more...

  • Toll and Toll-Like Receptors:by Tina Rich

    Springer US 2007; US$ 184.63

    Toll Receptors and the Renaissance of Innate Immunity Elizabeth H. Bassett and Tina Rich Overview n the last few pages of Immunology: The Science of Self-Nonself Discrimination Jan Klein ponders on what he would study if he were to start over in the lab. ^ Dismissing the I antibody, MHC, the T-cell and parasitology, he considers instead the phylogeny... more...

  • Principles and Methods for Assessing Autoimmunity Associated with Exposure to Chemicalsby WHO

    World Health Organization 2006; US$ 50.00

    This new volume in the Environmental Health Criteria series provides a framework for the evaluation of the role of chemical risk factors in the development of autoimmune diseases. In addition to a general introduction to autoimmune mechanisms and clinical expression of autoimmune diseases, a discussion of mechanisms of chemical-associated autoimmune... more...

  • Immunologyby Nandini Shetty

    New Age International Pvt. Ltd., Publishers 2005; US$ 20.00

    In this text, the author has tried to unfold before the student, the essence of immunology from its historic beginnings, to the understanding of basic concepts of host defence and onto the many clinical applications of this science. Immunology: Introductory Textbook, covers the topics of Immunobiology, Immunoglobulins, Immuno-response Mechanisms, Transplantation... more...

  • Neonatal Immunityby Constantin Bona

    Humana Press 2007; US$ 216.14

    A critical review of the classic, as wells as most recent-and quite seminal-findings concerning the phenotypic and molecular characteristics of both fetal and neonatal B and T cells, the cells that mediate antibody and cellular immune responses in newborns and infants. Dr. Bona shows how the antibody response of neonates is modulated by maternal antibodies... more...