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- Landes Bioscience 2006; US$ 149.00
Interleukin-10 (IL-10) is regarded as an immune suppressant cytokine. This reputation is due to the experimental observation that IL-10 decreases the function of antigen presenting cells and T helper 1 type immune responses. Surprisingly, however, IL-10 has potent anti-cancer effects since most experimental models demonstrate immune-mediated anti-tumor... more...
- Springer-Verlag New York Inc 2006; US$ 209.00
Illustrates how research advances our understanding of autoimmune disease mechanisms and identifies novel therapeutic targets that provide a hope for effective treatments. This book contains a number of advances in unraveling autoimmune reactions and the resulting armory of experimental immunotherapies for controlling autoimmune reactions. more...
- Taylor & Francis 2007; US$ 179.95
Written for professionals in biomedical research, Making and Using Antibodies: A Practical Handbook presents methods for the production, characterization, and use of antibodies. It takes readers step-by-step from antigen preparation to immunizations, adjuvants, screening, purification, storage, and application. Introductory material preceding each... more...
- CABI 2002; US$ 120.00
This text provides a review of the roles of specific nutrients in maintaining the immune response and host protection against infection. It also considers the influence of various factors, such as exercise and ageing, on the interaction between nutrition and immune function more...
- Springer-Verlag Berlin and Heidelberg GmbH & Co. KG 2006; US$ 249.00
The B lymphocyte lineage represents an important paradigm for exploring the molecular mechanisms underlying cell fate specification, differentiation and cellular activation. Major advances have been achieved in our understanding of the transcriptional control of early B cell development and terminal plasma cell differentiation. more...
- Springer-Verlag New York Inc 2007; US$ 189.00
Developments made in understanding various genetic and epigenetic regulatory processes that are critical for the generation of B cell repertoires include the role of chromatin regulation and nuclear organization in understating the IgH gene regulation. This work explains the role and mechanism of DNA repair proteins in somatic hypermutation. more...
- Springer 2006; US$ 99.00
Presents a portrayal of the life and achievements of Georges Kohler, who at age 38 shared a 1984 Nobel Prize with NK Jerne and C Milstein for inventing the technique that generates monoclonal antibodies. This scientific biography explains Kohler's pivotal discovery and its momentous influence on research, medicine and the biotech industry. more...
- Springer 2006; US$ 199.00
TNF-alpha plays a crucial role in the pathogenesis of many chronic inflammatory diseases. Elevated levels of TNF-alpha have been demonstrated in Crohn's disease, psoriasis, psoriatic arthritis, and rheumatoid arthritis, suggesting a role for TNF-alpha in their pathogenesis. Although TNF-alpha plays a critical role in the activation of innate and... more...
- Springer 2006; US$ 219.00
Deals with the description of the role of chemokines in immune response and underlines potential targets of therapeutical intervention. This book offers a series of contributions of the various challenging aspects of lymphocyte migration in homeostasis and in disease. more...
- Springer-Verlag Berlin and Heidelberg GmbH & Co. KG 2007; US$ 189.00
There is increasing evidence that the CD1 system has been conserved throughout mammalian evolution and is capable of presenting structurally diverse diacyglycerol, sphingolipid, polyisoprenol and lipopeptide antigens. These features of CD1 antigen presentation systems now point to a new and expanded view of the natural function of ab T cells, which... more...