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- Springer-Verlag New York Inc 2007; US$ 219.00
Developments made in understanding various genetic and epigenetic regulatory processes that are critical for the generation of B cell repertoires include the role of chromatin regulation and nuclear organization in understating the IgH gene regulation. This work explains the role and mechanism of DNA repair proteins in somatic hypermutation. more...
- Springer-Verlag Berlin and Heidelberg GmbH & Co. KG 2007; US$ 219.00
There is increasing evidence that the CD1 system has been conserved throughout mammalian evolution and is capable of presenting structurally diverse diacyglycerol, sphingolipid, polyisoprenol and lipopeptide antigens. These features of CD1 antigen presentation systems now point to a new and expanded view of the natural function of ab T cells, which... more...
- Springer-Verlag Berlin and Heidelberg GmbH & Co. KG 2006; US$ 289.00
The B lymphocyte lineage represents an important paradigm for exploring the molecular mechanisms underlying cell fate specification, differentiation and cellular activation. Major advances have been achieved in our understanding of the transcriptional control of early B cell development and terminal plasma cell differentiation. more...
- Springer-Verlag New York Inc 2007; US$ 259.00
Focuses on the signaling mechanisms and biology of the prototypic death receptor Fas, also called CD95 or APO-1. This book aims to provide the reader with a survey of the various aspects of Fas biology and the open questions of the field are addressed. It is intended for Ph D and post-doctoral students starting to work in the field. more...
- Springer 2007; US$ 259.00
Discusses the relationship between hosts and parasites. This book contains detailed descriptions of the immune system and the microbial world as well as methodological and conceptual clarifications. It is of interest not only to biologists, medical scientists, physicians and philosophers of science, but also microbiologists and immunologists. more...
- Springer 2006; US$ 199.00
Emphasizing a global approach to the analysis of T cell mediated target/host interactions at the systemic and the peripheral level when such interactions are supposed to occur, this book provides a critical assessment of the assays that have been used for the monitoring of antigen-specific immune responses. more...
- Springer-Verlag New York Inc 2007; US$ 149.00
Reviews how mathematics can be used in combination with biological data in order to improve understanding of how the immune system works. This book also provides both an introduction to the field of mathematical immunology, and an overview of many topics which are subjects of research, covering a variety of immunological topics. more...
- Springer-Verlag Berlin and Heidelberg GmbH & Co. KG 2006; US$ 239.00
The ethiopathologies of autoimmune diseases are complex. A broad variety of cell types and gene products are involved. This book explores clinical and experimental evidence suggesting that the importance of an individual factor changes during the course of the disease. more...
- Springer 2006; US$ 99.00
Presents a portrayal of the life and achievements of Georges Kohler, who at age 38 shared a 1984 Nobel Prize with NK Jerne and C Milstein for inventing the technique that generates monoclonal antibodies. This scientific biography explains Kohler's pivotal discovery and its momentous influence on research, medicine and the biotech industry. more...
- Springer 2006; US$ 239.00
TNF-alpha plays a crucial role in the pathogenesis of many chronic inflammatory diseases. Elevated levels of TNF-alpha have been demonstrated in Crohn's disease, psoriasis, psoriatic arthritis, and rheumatoid arthritis, suggesting a role for TNF-alpha in their pathogenesis. Although TNF-alpha plays a critical role in the activation of innate and... more...