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- Springer Basel 2012; US$ 259.00
MMPs are involved in numerous biological processes, fostering tissue degradation resulting in pathologies from osteoarthritis to tumor metastasis. This book focuses on the latest quantitative research into the endogenous inhibitors that disrupt MMP activity. more...
- Springer Berlin Heidelberg 2010; US$ 299.00
High quality leads provide the foundation for the discovery of successful clinical development candidates, and therefore the identi?cation of leads is an essential part of drug discovery. The process for the identi?cation of leads generally starts with the screening of a compound collection, either an HTS of a relatively large compound collection (hundreds... more...
- Springer International Publishing 2014; US$ 189.00
This volume focuses on the role of sphingosine-1-phosphate (S1P) and its analogs in the induced sequestration of lymphocytes in secondary lymphoid organs or in the microenvironment of tissues involved in infection or autoimmune disease. Initial chapters define the pathways to understand S1P signaling. They cover the organization of signaling systems,... more...
- Springer Berlin Heidelberg 2005; US$ 29.95
6 Therapie-Sicherheit für die Kitteltasche! Die bearbeitete und aktualisierte Neuauflage bietet Ihnen in bewährter Form eine kompetente Übersicht zur Pharmakotherapie psychischer Erkrankungen kompakte Darstellung aller Präparate ausführliche Bewertung jedes einzelnen Psychopharmakons tabellarische Übersicht zu allen klinisch wichtigen... more...
- Springer Berlin Heidelberg 2007; US$ 159.00
Optimal dose individualization has become more important in improving clinical efficacy and safety, given the variability in drug response, e.g., due to concurrent illnesses or co-medications. Therefore, the role of optimal dose finding in early clinical drug development so as to maximize successful clinical use is emphasized. The continued use of... more...
- Springer Berlin Heidelberg 2007; US$ 209.00
Genome- and proteome-based research is generating a significant increase in the number of available drug targets. Correspondingly there is an increasing need for novel, diverse compounds, particularly based on natural compounds, as screening resource. The purpose of the Ernst Schering Research Foundation Workshop 51 was to provide a forum for an... more...
- Springer Berlin Heidelberg 2008; US$ 549.00
Disease-relevant intracellular protein-protein interactions occurring at defined cellular sites possess great potential as drug targets. They permit highly specific pharmacological interference with defined cellular functions. Drugs targeting such interactions are likely to act with fewer side effects than conventional medication influencing whole... more...
- Springer Netherlands 2009; US$ 299.00
The eighth volume in the Proteases in Biology and Disease series, this text focuses on viral proteases, crucial prerequisites for viral entry into cells, and viral replication. It discusses viral proteases of key pathogenic viruses, such as AIDS and SARS. more...
- Springer Berlin Heidelberg 2011; US$ 279.00
Probiotic microorganisms have a long history of use, and their health benefits for hosts are well documented. This volume provides an overview of the current knowledge and applications of probiotics. Each chapter is written by one or more expert scientist. more...