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Statistical Aspects Of The Design And Analysis Of Clinical Trials

Statistical Aspects Of The Design And Analysis Of Clinical Trials by B S Everitt
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About 8000 clinical trials are undertaken annually in all areas of medicine, from the treatment of acne to the prevention of cancer. Correct interpretation of the data from such trials depends largely on adequate design and on performing the appropriate statistical analyses. In this book, the statistical aspects of both the design and analysis of trials are described, with particular emphasis on recently developed methods of analysis.

Contents: An Introduction to Clinical Trials; Treatment Allocation, the Size of Trials and Reporting Results; Monitoring Trial Progress: Outcome Measures, Compliance, Dropouts and Interim Analyses; Basic Analyses of Clinical Trials, the Generalized Linear Model and the Economic Evaluation of Trials; Simple Approaches to the Analysis of Longitudinal Data from Clinical Trials; Multivariate Normal Regression Models for Longitudinal Data from Clinical Trials; Models for Non-Normal Longitudinal Data from Clinical Trials; Survival Analysis; Bayesian Methods; Meta-Analysis.

Readership: Applied statisticians in medicine, researchers dealing with clinical trials and pharmaceutical companies.

World Scientific Publishing Company; January 2000
352 pages; ISBN 9781783262120
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Title: Statistical Aspects Of The Design And Analysis Of Clinical Trials
Author: B S Everitt; A Pickles