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Photopolymerizable Porous Polyorganophosphazenes

Degradable Matrices for Tissue Engineering

Photopolymerizable Porous Polyorganophosphazenes by Tamara Bernadette Aigner
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Tamara Bernadette Aigner designed a set of biocompatible and biodegradable poly(organophosphazenes). In order to tailor their biological and chemical properties, she further modified these macromolecules by adding functional moieties via thiol-ene chemistry. The author used the same photochemistry for crosslinking to obtain a mechanically stable network. She further altered the degradation rate of the matrix as well as the mechanical properties by adding blending agents and created a porous matrix, which is necessary for cell invasion and communication, by a newly developed photocrosslinking particulate-leaching method. Thus, a modular hybrid system was established which is able to adapt to different microenvironments based upon tissue type.
Springer Fachmedien Wiesbaden; March 2015
88 pages; ISBN 9783658093204
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Title: Photopolymerizable Porous Polyorganophosphazenes
Author: Tamara Bernadette Aigner
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