Schizophrenia

Evolution and Synthesis

by Steven M. Silverstein, Bita Moghaddam, Til Wykes, Steven M. Silverstein, Bita Moghaddam, Til Wykes, Angus MacDonald, William T. Carpenter, Leanne M. Williams, Aiden Corvin, Robert W. Buchanan, James L. Kennedy, Matcheri S. Keshavan, Louis Sass, Michèle Wessa, Peter B. Jones, Kristin S. Cadenhead, John McGrath, Andreas Meyer-Lindenberg, Craig Morgan, Michael O'Donovan, Robert Bittner, Heike Tost, Peter Uhlhaas, Aristotle Voineskos, Ashley Wilson, Akira Sawa, Patricio O'Donnell, Daniel Durstewitz, Jeremy K. Seamans, Kevin J. Mitchell, André Fenton, Jay A. Gingrich, Joshua A. Gordon, Wolfgang Kelsch, William A. Phillips, René S. Kahn, Kim T. Mueser, Wulf Rössler, Vera A. Morgan, Richard Keefe, Anil K. Malhotra, Karoly Nikolich, William Spaulding, Sharmili Sritharan,

Subject categories
ISBNs
  • 0262314614
  • 9780262019620
  • 9780262314619

Leading researchers address conceptual and technical issues in schizophrenia and suggest novel strategies for advancing research and treatment.

Despite major advances in methodology and thousands of published studies every year, treatment outcomes in schizophrenia have not improved over the last fifty years. Moreover, we still lack strategies for prevention and we do not yet understand how the interaction of genetic, developmental, and environmental factors contribute to the disorder. In this book, leading researchers consider conceptual and technical obstacles to progress in understanding schizophrenia and suggest novel strategies for advancing research and treatment.

The contributors address a wide range of critical issues: the construct of schizophrenia itself; etiology, risk, prediction, and prevention; different methods of modeling the disorder; and treatment development and delivery. They identify crucial gaps in our knowledge and offer creative but feasible suggestions. These strategies include viewing schizophrenia as a heterogeneous group of conditions; adopting specific new approaches to prediction and early intervention; developing better integration of data across genetics, imaging, perception, cognition, phenomenology, and other fields; and moving toward an evidence-based, personalized approach to treatment requiring rational clinical decision-making to reduce functional disability.

Contributors
Robert Bittner, Robert W. Buchanan, Kristin S. Cadenhead, William T. Carpenter, Jr., Aiden Corvin, Daniel Durstewitz, André A. Fenton, Camilo de la Fuente-Sandoval, Jay A. Gingrich, Joshua A. Gordon, Chloe Gott, Peter B. Jones, René S. Kahn, Richard Keefe, Wolfgang Kelsch, James L. Kennedy, Matcheri S. Keshavan, Angus W. MacDonald III, Anil K. Malhotra, John McGrath, Andreas Meyer-Lindenberg, Kevin J. Mitchell, Bita Moghaddam, Vera A. Morgan, Craig Morgan, Kim T. Mueser, Karoly Nikolich, Patricio O'Donnell, Michael O'Donovan, William A. Phillips, Wulf Rössler, Louis Sass, Akira Sawa, Jeremy K. Seamans, Steven M. Silverstein, William Spaulding, Sharmili Sritharan, Heike Tost, Peter Uhlhaas, Aristotle Voineskos, Michèle Wessa, Leanne M. Williams, Ashley Wilson, Til Wykes

  • The MIT Press; November 2013
  • ISBN 9780262314619
  • Read online, or download in secure PDF format
  • Title: Schizophrenia
  • Author: Steven M. Silverstein (ed.); Bita Moghaddam (ed.); Til Wykes (ed.); Steven M. Silverstein (contrib.); Bita Moghaddam (contrib.); Til Wykes (contrib.); Angus MacDonald (contrib.); William T. Carpenter (contrib.); Leanne M. Williams (contrib.); Aiden Corvin (contrib.); Robert W. Buchanan (contrib.); James L. Kennedy (contrib.); Matcheri S. Keshavan (contrib.); Louis Sass (contrib.); Michèle Wessa (contrib.); Peter B. Jones (contrib.); Kristin S. Cadenhead (contrib.); John McGrath (contrib.); Andreas Meyer-Lindenberg (contrib.); Craig Morgan (contrib.); Michael O'Donovan (contrib.); Robert Bittner (contrib.); Heike Tost (contrib.); Peter Uhlhaas (contrib.); Aristotle Voineskos (contrib.); Ashley Wilson (contrib.); Akira Sawa (contrib.); Patricio O'Donnell (contrib.); Daniel Durstewitz (contrib.); Jeremy K. Seamans (contrib.); Kevin J. Mitchell (contrib.); André Fenton (contrib.); Jay A. Gingrich (contrib.); Joshua A. Gordon (contrib.); Wolfgang Kelsch (contrib.); William A. Phillips (contrib.); René S. Kahn (contrib.); Kim T. Mueser (contrib.); Wulf Rössler (contrib.); Vera A. Morgan (contrib.); Richard Keefe (contrib.); Anil K. Malhotra (contrib.); Karoly Nikolich (contrib.); William Spaulding (contrib.); Sharmili Sritharan (contrib.); Julia Lupp (ed.)
  • Imprint: The MIT Press
Subject categories
ISBNs
  • 0262314614
  • 9780262019620
  • 9780262314619

In The Press

There is a wide agreement that schizophrenia remains poorly understood, and this book marvelously summarizes not only the clinical problem, but also the beginnings of a plan for solving it.

Journal of Clinical Psychiatry