Eye, Retina, and Visual System of the Mouse

by Leo M. Chalupa, Robert W. Williams, Priscilla K. Tucker, Aimee A. Wong, Richard E. Brown, Catherine A. Leamey, Dario A. Protti, Bogdan Dreher, Lawrence H. Pinto, John B. Troy, Frank Schaeffel, John S. Stahl, Glen T. Prusky, Robert M. Douglas, Vittorio Porciatti, Ernst R. Tamm, Antonia Kollenberger, Arkady Lyubarsky, Sergei S. Nikonov, L. Daniele, Edward N. Pugh Jr., Benjamin E. Reese, Enrica Strettoi, Stewart A. Bloomfield, Béla Völgyi, Maureen A. McCall, Neal S. Peachey, Ronald G. Gregg, Julie L. Coombs, Leo M. Chalupa, Christian-Albrecht May, Satchidananda Panda, Matthew S. Grubb, Tomoya Sakatani, Tadashi Isa, Andreas Burkhalter, Quanxin Wang, Barbara L. Finlay, Barbara Clancy, Michael L. Robinson, Michael R. Powers, Deepak Lamba, Branden Nelson, Mike O. Karl, Thomas A. Reh, Michael A. Dyer, Xiuqian Mu, William H. Klein, Lucia Galli-Resta, Maria Cristina Cenni, Marla B. Feller, Aaron G. Blankenship, Ning Tian, Ursula C. Dräger, Tuanlian Luo, Elisabeth Wagner, Lynda Erskine, Hannah Thompson, Timothy J. Petros, Carol A. Mason, Jeffrey Goldberg, William Guido, Chinfei Chen, Mark Hübener, Sonja Hofer, Thomas D. Mrsic-Flogel, Alesssandro Sale, Nicoletta Berardi, Lamberto Maffei, Mikhail Y. Frenkel, Mark F. Bear, Gareth R. Howell, Jeffrey K. Marchant, Simon W. M. John, Jochen Graw, Linda Hazlett, Rachel R. Caspi, Wolfgang Berger, Janet R. Sparrow, So R. Kim, Young P. Jang, Jilin Zhou, Rose A. Gubitosi-Klug, Timothy S. Kern, Jonathan Stone, Krisztina Valter, Michael Danciger, Bo Chang, Tudor C. Badea, Jeremy Nathans, Shannon E. Boye, Sanford L. Boye, William W. Hauswirth, Takahiko Matsuda, Constance Cepko, Dennis Rice, Patsy M. Nishina, Juergen K. Naggert, Eldon E. Geisert, Robert W. Williams, Sunil K. Parapuram, Anand Swaroop, Michael I. Dorrell, Martin Friedlander, Shivalingappa K. Swamynathan, Joram Piatigorsky, Wolfgang Hoehenwarter, Peter R. Jungblut, John C. Saari,

Subject categories
ISBNs
  • 0262308525
  • 9780262033817
  • 9780262308526
A comprehensive guide to current research, reflecting recent technical breakthroughs that have established the usefulness of the mouse model as part of a bilateral exchange between experimental and clinical research.

Recent years have seen a burst of studies on the mouse eye and visual system, fueled in large part by the relatively recent ability to produce mice with precisely defined changes in gene sequence. Mouse models have contributed to a wide range of scientific breakthroughs for a number of ocular and neurological diseases and have allowed researchers to address fundamental issues that were difficult to approach with other experimental models. This comprehensive guide to current research captures the first wave of studies in the field, with fifty-nine chapters by leading scholars that demonstrate the usefulness of mouse models as a bridge between experimental and clinical research. The opening chapters introduce the mouse as a species and research model, discussing such topics as the mouse's evolutionary history and the mammalian visual system. Subsequent sections explore more specialized subjects, considering optics, psychophysics, and the visual behaviors of mice; the organization of the adult mouse eye and central visual system; the development of the mouse eye (including comparisons to human development); the development and plasticity of retinal projections and visuotopic maps; mouse models for human eye disease (including glaucoma and cataracts); and the application of advanced genomic technologies (including gene therapy and genetic knockouts) to the mouse visual system. Readers of this unique reference will see that the study of mouse models has already demonstrated real translational prowess in vision research.

  • The MIT Press; July 2008
  • ISBN 9780262308526
  • Read online, or download in secure PDF format
  • Title: Eye, Retina, and Visual System of the Mouse
  • Author: Leo M. Chalupa (ed.); Robert W. Williams (ed.); Priscilla K. Tucker (contrib.); Aimee A. Wong (contrib.); Richard E. Brown (contrib.); Catherine A. Leamey (contrib.); Dario A. Protti (contrib.); Bogdan Dreher (contrib.); Lawrence H. Pinto (contrib.); John B. Troy (contrib.); Frank Schaeffel (contrib.); John S. Stahl (contrib.); Glen T. Prusky (contrib.); Robert M. Douglas (contrib.); Vittorio Porciatti (contrib.); Ernst R. Tamm (contrib.); Antonia Kollenberger (contrib.); Arkady Lyubarsky (contrib.); Sergei S. Nikonov (contrib.); L. Daniele (contrib.); Edward N. Pugh Jr. (contrib.); Benjamin E. Reese (contrib.); Enrica Strettoi (contrib.); Stewart A. Bloomfield (contrib.); Béla Völgyi (contrib.); Maureen A. McCall (contrib.); Neal S. Peachey (contrib.); Ronald G. Gregg (contrib.); Julie L. Coombs (contrib.); Leo M. Chalupa (contrib.); Christian-Albrecht May (contrib.); Satchidananda Panda (contrib.); Matthew S. Grubb (contrib.); Tomoya Sakatani (contrib.); Tadashi Isa (contrib.); Andreas Burkhalter (contrib.); Quanxin Wang (contrib.); Barbara L. Finlay (contrib.); Barbara Clancy (contrib.); Michael L. Robinson (contrib.); Michael R. Powers (contrib.); Deepak Lamba (contrib.); Branden Nelson (contrib.); Mike O. Karl (contrib.); Thomas A. Reh (contrib.); Michael A. Dyer (contrib.); Xiuqian Mu (contrib.); William H. Klein (contrib.); Lucia Galli-Resta (contrib.); Maria Cristina Cenni (contrib.); Marla B. Feller (contrib.); Aaron G. Blankenship (contrib.); Ning Tian (contrib.); Ursula C. Dräger (contrib.); Tuanlian Luo (contrib.); Elisabeth Wagner (contrib.); Lynda Erskine (contrib.); Hannah Thompson (contrib.); Timothy J. Petros (contrib.); Carol A. Mason (contrib.); Jeffrey Goldberg (contrib.); William Guido (contrib.); Chinfei Chen (contrib.); Mark Hübener (contrib.); Sonja Hofer (contrib.); Thomas D. Mrsic-Flogel (contrib.); Alesssandro Sale (contrib.); Nicoletta Berardi (contrib.); Lamberto Maffei (contrib.); Mikhail Y. Frenkel (contrib.); Mark F. Bear (contrib.); Gareth R. Howell (contrib.); Jeffrey K. Marchant (contrib.); Simon W. M. John (contrib.); Jochen Graw (contrib.); Linda Hazlett (contrib.); Rachel R. Caspi (contrib.); Wolfgang Berger (contrib.); Janet R. Sparrow (contrib.); So R. Kim (contrib.); Young P. Jang (contrib.); Jilin Zhou (contrib.); Rose A. Gubitosi-Klug (contrib.); Timothy S. Kern (contrib.); Jonathan Stone (contrib.); Krisztina Valter (contrib.); Michael Danciger (contrib.); Bo Chang (contrib.); Tudor C. Badea (contrib.); Jeremy Nathans (contrib.); Shannon E. Boye (contrib.); Sanford L. Boye (contrib.); William W. Hauswirth (contrib.); Takahiko Matsuda (contrib.); Constance Cepko (contrib.); Dennis Rice (contrib.); Patsy M. Nishina (contrib.); Juergen K. Naggert (contrib.); Eldon E. Geisert (contrib.); Robert W. Williams (contrib.); Sunil K. Parapuram (contrib.); Anand Swaroop (contrib.); Michael I. Dorrell (contrib.); Martin Friedlander (contrib.); Shivalingappa K. Swamynathan (contrib.); Joram Piatigorsky (contrib.); Wolfgang Hoehenwarter (contrib.); Peter R. Jungblut (contrib.); John C. Saari (contrib.); John W. Crabb (contrib.)
  • Imprint: The MIT Press
Subject categories
ISBNs
  • 0262308525
  • 9780262033817
  • 9780262308526

In The Press

This timely book provides an outstanding resource for both beginners and experts.... Of particular note is the book's final section on advanced techniques, which is filled with practical 'how-to' advice. Be warned: your colleagues down the hall will borrow this book shamelessly. My copy went missing more than once.

Markus Meister, The Quarterly Review of Biology

Subject categories
ISBNs
  • 0262308525
  • 9780262033817
  • 9780262308526