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Urological Oncology

Urological Oncology by Daniel Nachtsheim
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This book devotes three chapters to the treatment of prostatic cancer, the most common tumor in men, and presents the three points of view for treatment of this complex issue. For localized disease, it has long been debated whether surgery or radiation is the best treatment. There are two good treatments, and the chapters outline which treatment may be suitable for the individual. For advanced disease, androgen deprivation has stood the test of time, and refinement of depriving prostate cancer of its growth factor, androgens, has been a major advance, though not curative. Recent research in advanced prostate cancer appears promising and will focus on non-hormonal factors such as gene therapy, prolongation of androgen sensitivity, and molecular triggers to induce apoptosis.

This book also reviews the major urological tumors and by and large supports the idea that early detection and surgical removal of the tumor results in long-term survival. The chapters on bladder and urinary collecting system tumors emphasize that superficial disease is common and may be treated by surgical excision endoscopically and treatment with topical chemotherapy and immune therapy such as BCG. Testis tumors demonstrate the success with surgical excision and chemotherapy, and what was considered a fatal tumor 25 years ago is now within the realm of cure in most cases. Chapter 7 on urinary diversions shows that recreation and reconstruction of the urinary system with bowel segments has many ramifications and can result in successful reconstruction without the need for ostomies. Urological oncology is meant to be a quick read for the student or practitioner who needs an overall grasp of the organ system in question, and should give the reader a refined view of the problem and treatment in less than 1 hour reading per chapter.

Landes Bioscience; January 2003
147 pages; ISBN 9781570597688
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Title: Urological Oncology
Author: Daniel Nachtsheim