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Unconventional Electron Microscopy for Molecular Structure Determination

by W. Hoppe(ed.) ; R. Mason(ed.)
Unconventional Electron Microscopy for Molecular Structure Determination by W. Hoppe
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Generally it is not sufficiently appreciated that electron microscopy is in fact a diffraction method. In essential aspects electron microscopes are more closely related to X-ray diffracto· meters than to light microscopes. In electron microscopes monochromatized radiation and coherent illumination (never used in light microscopy) correspond in X-ray diffractometers to the primary beam with a small divergence. Imaging ina general sense can take place in interference experiments between a primary beam and a scattered beam, or between diffe­ rent deflected scattered beams. This leads to the realization of an old dream in diffracto­ metry, namely to a general experimental solution of the "phase problem". The most im­ pressive analogy, however, concerns the potential of the electron microscope as a tool for structure determination (where the radiation wavelenght is smaller than the atomic distan­ ces). It was therefore considered timely to treat this topic in this series. It was a fortunate cioncidence that in 1976 a Workshop on "Unconventional Electron Microscope Methods for the Investigation of Molecular Structures" (sponsored by the European Molecular Biology Organisation, the Deutsche Forschungsgemeinschaft and the Max-Planck-Gesell­ schaft) took place, and that most speakers presenting introductory lectures agreed to publish their contributions in an expanded version in this volume. This volume is thus not a symposium report in the usual sense since it contains the majority of these introductory lectures only.
Vieweg+Teubner Verlag; July 2013
227 pages; ISBN 9783322863621
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Title: Unconventional Electron Microscopy for Molecular Structure Determination
Author: W. Hoppe; R. Mason
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