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Focus on Bio-Image Informatics

Focus on Bio-Image Informatics by Winnok H. De Vos
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Meticulous observation and faithful documentation of small-scale biological phenomena have laid the foundation for modern cell and developmental biology. Invaluable information has been garnered on the morphological rearrangements that accompany crucial decision points such as cell division, differentiation and embryonic development. Even today, interpretation and annotation of microscopy images offers an elegant and convincing way of proving scientific observations.

However, in an era of omics, life science is becoming evermore quantitative. This also holds true for microscopy. On the quest towards quantitative biology and systems microscopy, manual microscopic documentation makes way for the standardized, high-throughput workflows that typify molecular platforms. And whilst the complexity of the biological processes under investigation inflates image data set dimensions, an unbiased assessment of the image content becomes an equally important challenge. A consequent need for novel strategies of image warehousing, reconstruction, and automated analysis has sparked the development of a new discipline, bio-image informatics, in which systems biology, modeling and computational analyses unite to provide robust, spatiotemporally defined information on the building blocks of life.

This volume of Advances Anatomy Embryology and Cell Biology focuses on the emerging field of bio-image informatics, presenting novel and exciting ways of handling and interpreting large image data sets. A collection of focused reviews written by key players in the field highlights the major directions and provides an excellent reference work for both young and experienced researchers.

Springer International Publishing; May 2016
277 pages; ISBN 9783319285498
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Title: Focus on Bio-Image Informatics
Author: Winnok H. De Vos; Sebastian Munck; Jean-Pierre Timmermans
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