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Applied Surrogate Endpoint Evaluation Methods with SAS and R by Ariel Alonso
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An important factor that affects the duration, complexity and cost of a clinical trial is the endpoint used to study the treatment’s efficacy. When a true endpoint is difficult to use because of such factors as long follow-up times or prohibitive cost, it is sometimes possible to use a surrogate endpoint that can be measured in a more convenient or cost-effective way. This book focuses on the use of surrogate endpoint evaluation methods in practice, using SAS and R.

CRC Press; November 2016
396 pages; ISBN 9781482249378
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Title: Applied Surrogate Endpoint Evaluation Methods with SAS and R
Author: Ariel Alonso; Theophile Bigirumurame; Tomasz Burzykowski; Marc Buyse; Geert Molenberghs; Leacky Muchene; Nolen Joy Perualila; Ziv Shkedy; Wim Van der Elst
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