The Leading eBooks Store Online 4,272,009 members ⚫ 1,419,367 ebooks

New to eBooks.com?

Learn more

Smart External Stimulus-Responsive Nanocarriers for Drug and Gene Delivery

Smart External Stimulus-Responsive Nanocarriers for Drug and Gene Delivery by Mahdi Karimi
Buy this eBook
US$ 36.00
(If any tax is payable it will be calculated and shown at checkout.)
The concept of smart drug delivery vehicles involves designing and preparing a nanostructure (or microstructure) that can be loaded with a cargo, this can be a therapeutic drug, a contrast agent for imaging, or a nucleic acid for gene therapy. The nanocarrier serves to protect the cargo from degradation by enzymes in the body, to enhance the solubility of insoluble drugs, to extend the circulation half-life, and to enhance its penetration and accumulation at the target site. Importantly, smart nanocarriers can be designed to be responsive to a specific stimulus, so that the cargo is only released or activated when desired. In this volume we cover smart nanocarriers that respond to externally applied stimuli that usually involve application of physical energy. This physical energy can be applied from outside the body and can either cause cargo release, or can activate the nanostructure to be cytotoxic, or both. The stimuli covered include light of various wavelengths (ultraviolet, visible or infrared), temperature (increased or decreased), magnetic fields (used to externally manipulate nanostructures and to activate them), ultrasound, and electrical and mechanical forces. Finally we discuss the issue of nanotoxicology and the future scope of the field.
Morgan & Claypool Publishers; December 2015
155 pages; ISBN 9781681740102
Read online, or download in secure EPUB or secure PDF format
Title: Smart External Stimulus-Responsive Nanocarriers for Drug and Gene Delivery
Author: Mahdi Karimi; Parham Sahandi Zangabad; Amir Ghasemi; Michael R Hamblin
 
ISBNs
9781681740102
9781681741383
9781681742021