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Hedgehog signaling activation in human cancer and its clinical implications

by Jingwu Xie(ed.)
Hedgehog signaling activation in human cancer and its clinical implications by Jingwu Xie
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Understanding the role of hedgehog signaling in cancer is critically important for novel cancer therapeutics. The hedgehog pathway is a major pathway regulating cell differentiation, tissue polarity, stem cell maintenance and cell proliferation. It is known by now that activation of this pathway occurs in a variety of human cancer, including basal cell carcinomas (BCCs), medulloblastomas, leukemia, gastrointestinal, lung, ovarian, breast and prostate cancers. This book provides insightful views suitable for graduate students, medical students, undergraduate students, basic and clinical scientists, cancer patients as well as the general public.

Springer New York; April 2011
223 pages; ISBN 9781441984357
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Title: Hedgehog signaling activation in human cancer and its clinical implications
Author: Jingwu Xie
 
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