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  • Fluorescence In Situ Hybridization (FISH) - Application Guideby Thomas Liehr

    Springer Berlin Heidelberg 2008; US$ 183.45

    This application guide provides an overview of the principles and basic techniques of fluorescence in situ hybridization (FISH) and primed in situ hybridization (PRINS), which are successfully used to study many aspects of genomic behavior and alterations. more...

  • Benign and Pathological Chromosomal Imbalancesby Thomas Liehr

    Elsevier Science 2013; US$ 99.95

    Benign & Pathological Chromosomal Imbalances systematically clarifies the disease implications of cytogenetically visible copy number variants (CG-CNV) using cytogenetic assessment of heterochromatic or euchromatic DNA variants. While variants of several megabasepair can be present in the human genome without clinical consequence, visually distinguishing... more...

  • Small Supernumerary Marker Chromosomes (sSMC)by Thomas Liehr; UNIQUE

    Springer Berlin Heidelberg 2011; US$ 81.93

    With numerous case studies complementing the theoretical aspects of the subject, and focusing on genetic diagnostics as well as on prenatal and fertility-related genetic counseling, this book is the first of its kind and includes the latest research on sSMCs. more...

  • Uniparental Disomy (UPD) in Clinical Geneticsby Thomas Liehr; UNIQUE

    Springer Berlin Heidelberg 2014; US$ 91.72

    This book focus on genetic diagnostics for Uniparental Disomy (UPD), a chromosomal disorder defined by the exceptional presence of a chromosome pair derived from only one parent, which leads to a group of rare diseases in humans. First the molecular and cytogenetic background of UPD is described in detail; subsequently, all available information of... more...

  • FISH Technologyby Bernd W. Rautenstrauß; Thomas Liehr

    Springer Berlin Heidelberg 2012; US$ 122.30

    Fluorescence in situ hybridization (FISH) has been developed as a powerful technology which allows direct visualisation or localisation of genomic alterations. The technique has been adopted to a range of applications in both medicine, especially in the areas of diagnostic cytogenetics, and biology. Topics described in this manual include: FISH on... more...

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