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  • Gap Junction-Mediated Intercellular Signalling in Health and Diseaseby Gail Cardew

    Wiley 2008; US$ 144.00

    Gap junctions are key elements in communication between cells in multicellular organisms.  It is clear that their activity is essential for normal embryonic development and normal function in adult organs, although the individual roles of the proteins that form the channels (connexins) are not yet fully understood. The last few years have seen considerable... more...

  • T Cell Subsets in Infectious and Autoimmune Diseasesby Derek J. Chadwick; Gail Cardew

    Wiley 2008; US$ 157.50

    T cells are a specialized population of immune cells that aid the immune system in combating various types of invading pathogens. This book presents up-to-the-minute data on the role of T cells in autoimmune diseases. more...

  • Bacterial Responses to pHby Derek J. Chadwick; Gail Cardew

    Wiley 2008; US$ 144.00

    Microbial responses to acidic and alkaline pH are important in many areas of bacteriology. For example, the mechanisms of resistance to acidic pH are important in the understanding of the passage of human pathogens through the acid of the stomach; and an understanding of microbial degradation of alkaline industrial waste is important for the environment.... more...

  • Somatostatin and Its Receptorsby Derek J. Chadwick; Gail Cardew

    Wiley 2008; US$ 157.50

    This book describes a diverse analysis of the five somatostatin receptors; somatostatin gene regulation; promatostatin processing; mechanisms of signal transduction; and the design and use of somatostatin analogues, including their possible clinical implications. The book will provide a comprehensive summary of the cellular and molecular biology of... more...

  • Dental Enamelby Derek J. Chadwick; Gail Cardew

    Wiley 2008; US$ 154.80

    The molecular mechanisms and protein species associated with the mineralization of mature dental enamel are active areas of research. This book focuses on specific areas of research including the structural chemistry, protein biochemistry and genetics of enamel development. more...

  • Gramicidin and Related Ion Channel-Forming Peptidesby Derek J. Chadwick; Gail Cardew

    Wiley 2008; US$ 144.00

    Gramicidin channels have been studied intensively for more than 25 years.  They serve as model transport systems for large protein ion channels, since it is difficult to glean high-resolution structural information on the latter. This book includes contributions from virtually all the major scientists studying gramicidin channels and is the only compilation... more...

  • Epigeneticsby Derek J. Chadwick; Gail Cardew

    Wiley 2008; US$ 144.00

    Epigenetics pertains to the development of an organism from an undifferential cell, resulting in the successive formation and development of organs and parts that did not pre-exist in the fertilized egg. An exciting and stimulating volume which used the extensive knowledge of basic transcriptional control as a foundation to explore the more complex... more...

  • Development of the Cerebral Cortexby Gregory R. Bock; Gail Cardew

    Wiley 2008; US$ 157.50

    This book details the rapidly advancing research on the development of the cerebral cortex. Topics covered include: new physiological data showing patterns in developing cortical organization; abnormalities of cortical development associated with psychiatric disorders; and research on cell identity and regionalization of the cortex. more...

  • Telomeres and Telomeraseby Derek J. Chadwick; Gail Cardew

    Wiley 2008; US$ 159.30

    Telomeres and Telomerase Chairman: Sydney Brenner, 1997 Telomeres are the protective genetic elements located at the ends of chromosomes and are essential for correct chromosomal structure and function. They are not fully replicated by the conventional DNA polymerase system because DNA synthesis occurs only in the 5' to 3' direction and requires... more...

  • Oligonucleotides as Therapeutic Agentsby Derek J. Chadwick; Gail Cardew

    Wiley 2008; US$ 169.20

    The use of oligonucleotides as therapeutic agents rests upon their ability to interfere, in a sequence-specific manner, with the fundamental machinery of protein synthesis either by binding to the mRNAs transcribed from a gene or by binding directly to a target gene. This approach can be used not only for inhibition of the synthesis of host proteins... more...